Parkinsonism epidemiology and nosological structure in the Central - Western Ukraine
S. Moskovko G. Moskovko (Vinnitsa National Medical University, Vinnitsa, Ukraine)
Parkinsonism epidemiology was studied for the first time in period of 1995 - 2005 by method of the memory register in the Vinnitsa region (population of 17,874 persons) in the Central Western part of Ukraine. All diagnosed patients (2641 cases) were included. 244 persons had died during this period. Prevalence of a Parkinson's syndrome (direct method) in a population is estimated as 13,411 cases in 100,000 (14,513 for men and 1,249 for women). For urban population this parameter has made 12,615 cases (12,907 for men and 12,359 for women), and for rural – 14,152 cases (16,093 for men and 12,607 for women). The average estimation, in view of heterogeneity of the population and influence of socio-economic and medical factors, quality and availability of medical aid, had made was 15439±7183 per 100,000 (17,364±10,108 for man’s, 13,907±6014 for woman). Middle onset age of disease at men was higher (6584 ± 1083 years), than at women (6420 ± 10.55), p < 0,001. Annual incidence of disease is estimated as 121 new cases on 100,000.
Nosological structure was established in a cohort of 372 patients strictly according to existing diagnostic criteria. In 256 cases (68.72 %) the diagnosis of idiopathic PD is established. In sixteen cases (4.3 %) is established diagnosis of MSA, in eleven (2.96 %) - PSP, in five (1.34 %) - CBGD, in thirteen (3.5 %) - vascular Parkinsonism. In 36 cases (9.68 %) exact diagnosis to establish it was not possible. In 35 cases (9.41 %) was established essential tremor (diagnosis was change by movement disorders specialist). Thus, nosologic structure of Parkinsonism in the Ukrainian population is similar to anothers Caucasian populations in Europe and North America, while prevalence seems a little smaller.