15th International Congress
15th international congress

News Release

Tuesday, June 7, 2011
Media Contact:

Elizabeth Laur, (414) 276-2145, elaur@movementdisorders.org
MDS Press Room: Metro Toronto Convention Centre, South Building, Room 705

Note to media: See abstract 339

Apathy is independent from depression and dementia in Parkinson's disease

TORONTO - A study investigating the correlation between apathy, depression and dementia in Parkinson's disease was presented today at The Movement Disorder Society's 15th International Congress of Parkinson's Disease and Movement Disorders.

The study, led by Gabriel Robert, MD, of Rennes, France, reveals that apathy, a core characteristic of Parkinson's disease, is not related to depression and dementia in PD, and is also unrelated to motor aspects of the disease.

Forty-five non depressed and non demented PD patients were assessed using the Apathy Evaluation Scale (AES). Results showed the AES score was not correlated to motor scores or levodopa treatment. Imaging data were also analyzed with the Statistical Parametric Mapping 2.

Daniel Weintraub, MD, of the University of Pennsylvania, supports these findings by stating, "This research is significant for a few reasons. First, it further documents that abnormalities in prefrontal cortex, in this case metabolic derangements, may underlie the development of apathy in patients with Parkinson's disease. The PET imaging results from this study nicely complement the findings of studies of apathy in PD patients that have used structural imaging and neuropsychological testing. In addition, the exclusion of depressed patients in this study population is additional evidence that although apathy and depression in PD overlap to some extent, they are also distinct disorders."

About the 15th International Congress of Parkinson's Disease and Movement Disorders:
Meeting attendees are gathered to learn the latest research findings and state-of-the-art treatment options for Movement Disorders, including Parkinson's disease. More than 3,200 physicians and medical professionals from 74 countries will be able to view over 1,100 scientific abstracts submitted by clinicians from around the world.

About The Movement Disorder Society:
The Movement Disorder Society, an international society of over 3,000 clinicians, scientists, and other healthcare professionals, is dedicated to improving patient care through education and research. For more information about The Movement Disorder Society, visit www.movementdisorders.org.