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Journal CME

Journal CME 36.09: Cortical [18F]PI-2620 Binding Differentiates Corticobasal Syndrome Subtypes

Length:60 MinutesCME Credits:1Release Date:Sep 30, 2021

Expert / AdvancedJournal CME

Program Description

The Journal CME 36.09 article provided an investigation into the diagnostic value of the tau PET-ligand [18F]PI-2620 in patients with corticobasal syndrome.


  • Basic/Translational Neuroscience
  • Etiology & Pathophysiology
  • Parkinson Disease/Hypokinetic Movement Disorders


Carla Palleis, MD

Course Purpose

Journal CME highlights various articles covering relevant issues, developments and research topics in the area of movement disorders. Articles are selected from Movement Disorders, the official Journal of the International Parkinson and Movement Disorder Society.

Learning Objectives

Upon completion of this activity learners will be able to:

1. Understand the association of corticobasal syndrome with cerebral protein aggregates
2. Assess how imaging can be a useful biomarker for the evaluation of corticobasal syndrome
3. Evaluate the results and how [18F]PI-2620 may potentially serve for a differential diagnosis and for monitoring disease progression

Intended Audience

This activity is intended for physicians, fellows or other practitioners in the field of Movement Disorders with an emphasis on current practice trends.

Accreditation Credit

Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME). The International Parkinson and Movement Disorder Society is accredited by the ACCME to provide continuing medical education for physicians.


Credit Designation Statement

The International Parkinson and Movement Disorder Society designates this education activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

Method of Participation

Your chosen sessions must be attended in their entirety. Partial credit of individual sessions is not available. If you are seeking continuing education credit for a specialty not listed in the Accreditation Statement, it is your responsibility to contact your licensing/certification board to determine course eligibility for your board requirement.

Faculty Disclosure

All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available below. All relevant financial relationships have been mitigated in advance of this program.


Sara SchaeferCourse Director
Nothing to Disclose

Veronica SantiniReviewer
Grant: Insightec, Biogen, Roche / Genentech

Carla Palleis: Author
Nothing to disclose

Matthias Brendel: Author
Speaker honoraria from GE Healthcare and LMI and is an adviser of LMI

Anika FinzeAuthor
Nothing to disclose

Endy Weidinger: Author
Nothing to disclose

Kai Bötzel: Author
Nothing to disclose

Adrian Danek: Author
Nothing to disclose

Leonie Beyer: Author
Nothing to disclose

Alexander Nitschmann: Author
Nothing to disclose

Maike Kern: Author
Nothing to disclose

Gloria Biechele: Author
Nothing to disclose

Boris-Stephan Rauchmann: Author
Nothing to disclose

Jan Häckert: Author
Nothing to disclose

Matthias Höllerhage: Author
Nothing to disclose

Andrew W. Stephens: Author
Employee: LMI

Alexander Drzezga: Author
Nothing to disclose

Thilo van Eimeren: Author
Nothing to disclose

Victor L. Villemagne: Author
Nothing to disclose

Andreas Schildan: Author
Nothing to disclose

Henryk Barthel: Author
Nothing to disclose

Marianne Patt: Author
Nothing to disclose

Osama Sabri: Author
Research funding: LMI

German Imaging Initiative for Tauopathies (GII4T): Author
Nothing to disclose

Peter Bartenstein: Author
Nothing to disclose

Robert Perneczky: Author
Advisory board: Biogen; Consultant: Eli Lilly; Grant Recipient: Janssen Pharmaceutica and Boehringer Ingelheim; Speaker honoraria: Janssen-Cilag, Pfizer, and Biogen

Christian Haass: Author
Chief Scientific Adviser of ISAR Biosciences; Collaboration: DENALI Therapeutics

Johannes Levin: Author
Speaker fee: Bayer Vital; Consulting fee: Axon Neuroscience; Author fee: Thieme medical publishers and W. Kohlhammer GmbH medical publishers; Nonfinancial support: AbbVie, Part-time CMO from MODAG GmbH, all outside the submitted work

Günter U. Höglinger: Author
Research collaboration: Prothena; Consultant: AbbVie, AlzProtect, Asceneuron, Biogen, Biohaven, Lundbeck, Novartis, Roche, Sanofi, UCB; Honoraria: AbbVie, Bial, Biogen, Bristol Myers Squibb, Roche, Teva, UCB, and Zambon; Patent: PERK Activation for the Treatment of Neurodegenerative Diseases (PCT/EP2015/068734)

Staff Disclosure

MDS staff members involved with the planning, development, and review of the content for this activity have no relevant affiliations or financial relationships to disclose.

Hardware and Software Requirements

1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.
2. Compatible with Windows PC and MAC (256 MB of RAM or higher)
3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher
4. Adobe Flash Player 12.0 (or higher).
5. Adobe Reader to print certificate.

Contact Us

MDS Education

MDS Secretariat Liaison

Ericka Blackford


All individuals in control of content for this course are required to disclose all relevant financial relationships with commercial interests as defined by the ACCME.

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