MDS Staff Liaison: Amber Flatland
Task Force Purpose
Multiple system atrophy (MSA) is diagnosed typically half way through its clinical course according to the widely accepted revised consensus criteria in 2008. A validation exercise of the second consensus criteria showed a sensitivity for MSA diagnosis of 41% for possible and 18% for probable at first neurological visit, whereas at last visit these figures were 92% and 63% respectively.
With an anticipated emergence of novel disease modifying treatments, it is important to increase the specificity and overcome the poor sensitivity of the existing criteria in early stages. Therefore revisiting the current set of diagnostic criteria for MSA becomes a research priority.
The MSA Criteria Revision Task Force will aim to achieve a revision of the second consensus criteria for the diagnosis of MSA.
Expert Consultants (Non-Voting):
Maria Theresa Pellecchia
Neuropathology Support Team (Non-Voting):
Junior Executive Team (Non-Voting):
Giovanna Calandra Bounaura