MDS Podcast

A cross-sectional study of PPMI participants using alpha-synuclein seed amplification as a biomarker

Mon, 12 Jun 2023 00:00:00 EST

In this episode Dr. Tiago Outeiro talks with Dr. Andrew Siderowf about the exciting new results in his most recent publication on alpha-synuclein seed amplification assay. Read the article.

A lifetime of experiences and learnings - MDS 40th Anniversary

Mon, 08 Dec 2025 00:00:00 EST

To celebrate the 40th Anniversary of the MDS, Dr. Michele Matarazzo sits down with two key leaders of the MDS Pan-American section, Dr. Cynthia Comella and Dr. Oscar Gershanik. Together they discuss how they got involved in the society, what they are most proud of, and what the Society means to them, both professionally and personally.

A new pathway to find structural variations in inherited neurological cases - the SCA4 example

Mon, 29 Apr 2024 00:00:00 EST

Dr. Sarah Camargos interviews Dr. Zhonghbo Chen and Prof. Henry Houlden, first and senior author of a MDJ paper exploring a GGC repeat expansion in the ZFHX3 gene associated with spinocerebellar ataxia type 4. They describe a criative methodology to find a gene in a family with a Swedish ancestry.
Journal CME is available until April 04, 2025 Read the article.

A post-hoc analysis of the Prasinezumab trial in early Parkinson's disease

Mon, 15 Jul 2024 00:00:00 EST

Dr. Gennaro Pagano discusses the findings of the post-hoc analysis of the PASADENA trial, a study using the monoclonal antibody Prasinezumab directed at aggregated α-synuclein, where motor progression trajectories differed between active and placebo groups. Read article »

Acetylcholine nuclei atrophy predicts gait changes in Parkinson's disease

Mon, 01 Mar 2021 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Nicola Ray on a recently published article that demonstrates a relationship between changes in cholinergic nuclei in MRI and future gait disorders in Parkinson's disease. Read the article

Achievements and future goals: An interview with MDS President • 2025 MDS Congress

Mon, 20 Oct 2025 00:00:00 EST

Dr. Victor Fung reflects on his term as MDS President and his appreciation for the accomplishments that were achieved. He further discusses his future hopes and goals of the Society and the #mdscongress.

Advanced therapies for Parkinson's disease: Are they all the same?

Fri, 22 Mar 2019 00:00:00 EST

Dr. K. Ray Chaudhuri discusses with Dr. Michele Matarazzo his article on the differences between subthalamic nucleus DBS, intrajejunal levodopa and apomorphine infusion in Parkinson's, published in the March 2019 issue of the Movement Disorders journal. Read the article

Advancements in Dystonia Treatments | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

What innovations in dystonia treatments do we have to look forward to? Dr. Mark Edwards sits down with Dr. Sarah Camargos to answer that vary question.

Advances in Supranuclear Palsy Research | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

Despite the challenge of studying rare conditions like PSP, Dr. Yaroslau Compta discusses with Dr. Eduardo de Pablo-Fernández how leaps forward in recent advances could make us rethink the way we approach the condition.

An interview with Claudia Trenkwalder | Congress 2021

Thu, 30 Sep 2021 00:00:00 EST

Dr. Sara Schaefer discusses with Dr. Claudia Trenkwalder the 2021 Virtual MDS Congress, her tenure as the MDS president, and her hopes for the future of the MDS.

An Interview with MDS President Francisco Cardoso | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

MDS President Francisco Cardoso shares with Dr. Michele Matarazzo the important takeaways from this year's Congress that will shape the future of movement disorders and the Society.

An online mindfulness-based group intervention for tics

Mon, 21 Oct 2024 00:00:00 EST

Dr. Hannah E. Reese and Mr. W. Alan Brown discuss their pilot study of a mindfulness-based group virtual intervention for tic disorders, that was co-developed with patients.
Journal CME is available until August 21, 2025 Read the article.

Antibiotics and Parkinson's disease

Tue, 31 Mar 2020 00:00:00 EST

In this issue Dr. Filip Sheperjans shares the results of the article published in the March 2020 issue of the Movement Disorders journal on the effect of antibiotic exposure on the risk of developing Parkinson's disease. Read the article

Anti-inflammatory drugs use impacts the risk of developing PD in LRRK2 mutation carriers

Mon, 09 Nov 2020 00:00:00 EST

Dr. Marta San Luciano shares the main findings of the recently published article on the impact of non-steroidal anti-inflammatory drugs use on the risk of developing PD in a large LRRK2 mutation carriers cohort. Read the article

Anxiety in parkinson's disease and its correlates in mri-based functional connectivity

Mon, 01 Feb 2021 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Rosa De Micco on the functional MRI correlates of anxiety in Parkinson's disease, highlighting the main results of the article she recently published on the topic in the Movement Disorders journal.Read the article

Approach to neuroimaging in Parkinsonisms

Mon, 17 Jan 2022 00:00:00 EST

Dr. Sara Schaefer discusses with Professor Antonio Strafella and Dr. Cecilia Peralta their work from the MDS Neuroimaging Study Group published in Movement Disorders Clinical Practice on a "Pragmatic Approach on Neuroimaging Techniques for the Differential Diagnosis of Parkinsonisms." Read the article

Approach to reviewing a review article

Mon, 16 May 2022 00:00:00 EST

For the sixth episode of the special series focused on the peer review process, Dr. Shweta Prasad speaks with Prof. Christine Klein to discuss the approach to reviewing a review article.

Are hyposmia and REM sleep behavior disorder reliable indicators of Lewy body pathology?

Mon, 10 Mar 2025 00:00:00 EST

There is an important role for cost-effective clinical biomarkers in the diagnosis of Parkinson's disease. Dr. Eduardo de Pablo-Fernández and Dr. Cecilia Tremblay discuss how accurate hyposmia and REM sleep behavior disorder can predict Lewy pathology in a non-selected population using data from the Arizona clinicopathological study on Aging and Neurodegeneration. Read the article.

Artificial intelligence in the diagnostic approach of chronic ataxias

Mon, 07 Jul 2025 00:00:00 EST

Dr. Hugo Morales interviews Drs. Malco Rossi and Lucas Alessandro about their work on an AI-powered virtual assistant designed to aid in the diagnosis of chronic ataxias. They discuss how the assistant performed when put to the test, evaluating its diagnostic accuracy head-to-head against movement disorder experts.
Journal CME is available until May 21, 2026
Read the article.

Ataxia Series: Deconstructing late-onset idiopathic ataxia

Mon, 30 Mar 2026 00:00:00 EST

Cases of late-onset cerebellar ataxias are a challenge for neurologists. In this episode Dr. Orlando Barsottini and Dr. José Luiz Pedroso discuss new advances on the investigation of late-onset cerebellar ataxias and identification of new genes.

Ataxia Series: The ataxia exam - Phenomenology, classification, and a practical diagnostic roadmap

Mon, 16 Mar 2026 00:00:00 EST

In this episode, Dr. Orlando Barsottini and Dr. Bart van de Warrenburg discuss the importance of precise neurological examination and classification of ataxias. The further discuss the rational etiological investigation for cases of ataxia and how to utilize different clinical assessments.

Atypical Parkinsonisms | Congress 2019

Wed, 06 Nov 2019 00:00:00 EST

As part of the MDS Congress 2019 Special Issue, Dr. Michele Matarazzo interviews Dr. Gesine Respondek about atypical parkinsonisms, focusing on the MDS activities to advance in the knowledge and management of these diseases and facilitate clinical trials.

Autophagy in levodopa-induced dyskinesia: A new potential therapeutic target

Sat, 01 May 2021 00:00:00 EST

Dr. Michele Matarazzo interviews Prof. Gilberto Fisone about the role of autophagy in levodopa-induced dyskinesia. Read the article

Award Article: A Multi-Step Model of Parkinson's Disease Pathogenesis

Sat, 17 Sep 2022 00:00:00 EST

"A Multi-Step Model of Parkinson's Disease Pathogenesis" was awarded "Best Research Article of the Movement Disorders journal for 2022." Dr. Michele Matarazzo interviews the first author, Dr. Campbell Le Heron. Read the article

Award Article: Have we forgotten what tics are?

Thu, 31 Aug 2023 00:00:00 EST

In this special issue celebrating the Movement Disorders Clinical Practice journal Research Article of the Year 2023, Sara Schaefer discusses tic phenomenology in primary tic disorders vs. functional tic-like disorders with Dr. Tamara Pringsheim. Read the article »

Award Article: Long duration levodopa response and neuroplasticity in Parkinson’s disease

Thu, 31 Aug 2023 00:00:00 EST

In this special issue celebrating the Movement Disorders journal Research Article of the Year 2023, Sara Schaefer discusses with Dr. Mario Zappia the effects of the short vs long duration responses to levodopa on cortical excitability and neuroplasticity in response to motor learning tasks in early Parkinson’s disease patients. Read the article »

Award Replay: MDS Criteria for the diagnosis of Multiple System Atrophy: New features and implications

Sat, 17 Sep 2022 00:00:00 EST

A re-release of the episode featuring the recently-awarded "Best Review article of 2022 from the Movement Disorders journal" article, titled "The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy." Read the article.

Basic Science Updates in Movement Disorders | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

Which emerging areas of movement disorders research are set to advance in the coming years? And how is that already beginning to affect clinical care? Prof. Jose Obeso shares about this and other key scienctific shifts with Prof. Tiago Outeiro.

Better understanding functional movement disorders • 2024 MDS Congress

Mon, 07 Oct 2024 00:00:00 EST

Dr. Alexander Lehn breaks down functional movement disorders; what is happening in the brain, what are the potential risk factors and what future treatments and clinical trials we have to look forward to.

Bilateral focused ultrasound thalamotomy for essential tremor, is it safe?

Mon, 14 Mar 2022 00:00:00 EST

Prof. Andres Lozano shares the results of the phase 2 clinical trial showing safety and feasibility of the staged bilateral MR-guided focus ultrasound thalamotomy in 10 patients. Read the article.

Biomarker Updates: A conversation on biomarkers and diagnostics of Parkinson's disease and related disorders

Mon, 01 Apr 2024 00:00:00 EST

In this episode, Dr. David Burn shares his views with Prof. Tiago Outeiro on the topic of diagnostic and biomarkers in PD and atypical parkinsonism, and how these may impact the clinical practice. Recorded at the MDS-ES Focused Workshop: Diagnostic and Progression Biomarkers in Parkinson’s Disease and Atypical Parkinsonism, Feb. 29 - Mar. 02, 2024.

Biomarker Updates: Ongoing pharmacological developments in Parkinson’s disease and related disorders

Mon, 01 Apr 2024 00:00:00 EST

In this episode, Prof. Olivier Rascol provides an overview of his presentation at the MDS-ES Focused Workshop: Diagnostic and Progression Biomarkers in Parkinson’s Disease and Atypical Parkinsonism, and discusses his view on ongoing efforts for the development of novel therapeutic strategies for Parkinson's disease and related synucleinopathies.

Biomarker Updates: The immune system in Parkinson’s disease

Mon, 01 Apr 2024 00:00:00 EST

In this episode, Prof. Romero Ramos provides an overview of her presentation at the MDS-ES Focused Workshop: Diagnostic and Progression Biomarkers in Parkinson’s Disease and Atypical Parkinsonism, and discusses the role of the immune system in Parkinson's disease.

Biomarker Updates: The Parkinson's disease pandemic

Mon, 01 Apr 2024 00:00:00 EST

In this episode. Prof. Bas Bloem provides an overview of the topics covered in his lecture at the MDS-ES Focused Workshop: Diagnostic and Progression Biomarkers in Parkinson’s Disease and Atypical Parkinsonism, and discusses how biomarkers may help us identify patients and select adequate therapeutic strategies.

Biomarkers and basic science research • 2024 MDS Congress

Mon, 07 Oct 2024 00:00:00 EST

Prof. Brit Mollenhauer shares her excitement about basic science, including biomarker research, and how she believes MDS’s diversity can help foster more collaboration between clinicians and basic scientists.

Blinded RT-QuIC analysis of alpha-synuclein biomarker in skin tissue from Parkinson's disease patients

Wed, 01 Sep 2021 00:00:00 EST

Dr. Sara Schaefer speaks with Dr. Anumantha Kanthasamy about RT-QuIC from skin tissues as a potential new biomarker for Parkinson's disease. Read the article

Breaking down functional movement disorders • 2025 MDS Congress

Mon, 27 Oct 2025 00:00:00 EST

Functional movement disorders (FMDs) are the most common subgroup of functional neurological disorders. Prof. Selma Aybek breaks down current trends for FMDs, controversies, and treatment preferences, including implementing an interdisciplinary team.

Can dogs diagnose Parkinson's disease?

Mon, 14 Nov 2022 00:00:00 EST

Dr. Sarah Lidstone interviews Dr. Chang-Qing Gao & Prof. Ji-fung Guo about their recent research on the sensitivity of sniffer dogs for diagnosing Parkinson's disease. Read the article.

Celebrating the Parkinson's community

Fri, 11 Apr 2025 00:00:00 EST

On this special World Parkinson’s Day episode, Dr. Michele Matarazzo is joined by John Dean—speech-language pathologist and Chair of the MDS Allied Health Professionals Group—to explore the essential roles of care partners, allied health professionals, and the broader Parkinson’s community. From physiotherapists to family members, we shine a light on the many people who support those living with Parkinson’s disease every day. World Parkinson's Day

Chorea Series: Approach to patients with acquired choreas

Mon, 20 May 2024 00:00:00 EST

Dr. Ruth Walker and Dr. Molly Cincotta discuss causes of acquired chorea and approach to the work-up of a patient with an acquired chorea.

Chorea Series: Approach to patients with genetic choreas

Mon, 22 Apr 2024 00:00:00 EST

Dr. Ruth Walker invites Prof. Emilia Gatto and Dr. Kevin Peikert onto the MDS Podcast for the second episode of the Chorea Special series. Together they discuss the general approach to patients with chorea of genetic etiology, with specific clues to diagnosis in terms of neurological and other features. They also discuss the nomenclature of neuroacanthocytosis syndromes, specific clues to the diagnosis in the clinical presentation and laboratory findings.

Chorea Series: Exploring medical and surgical management for chorea

Mon, 03 Jun 2024 00:00:00 EST

Profs. Elena Moro and Ruth Walker discuss the management of chorea, including when this is appropriate. They focus on Huntington’s disease and the role of deep brain stimulation and other surgical interventions, in addition to medical management.

Chorea Series: Phenomenology of Chorea

Mon, 08 Apr 2024 00:00:00 EST

Guest editor Dr. Ruth Walker kicks off this special series on chorea by interviewing Prof. Joseph Jankovic on the phenomenology and his approach to the clinical examination of the patient with chorea.

Chorea Series: Update on therapies for Huntington's disease

Mon, 06 May 2024 00:00:00 EST

In the latest installment of the Chorea Special Series, Dr. Ruth Walker interviews Prof. Sarah Tabrizi about the current state of therapies for Huntington’s disease, and what is coming down the pipeline.

Clozapine in Parkinson's disease: Why, when and how?

Mon, 13 Feb 2023 00:00:00 EST

Clozapine is a antipsychotic drug that has been marketed for decades. In this interview, Dr. Friedman shares his thoughts on its utility in Parkinson's disease along with some practical advices on how to use it in the clinic. Read the article.

Cognitive and visuospatial abilities in dystonia

Tue, 01 Jun 2021 00:00:00 EST

Dr. Sara Schaefer speaks with Dr. Carlos Camargo about the non-motor and prodromal features of dystonia. Read the article

Collegiality and friendship - MDS 40th Anniversary

Mon, 08 Dec 2025 00:00:00 EST

To celebrate the 40th Anniversay of the MDS, Dr. Michele Matarazzo sits down with two key leaders of the MDS Asian Oceanian section, Prof. Carolyn Sue and Prof. Beomseok Jeon. Together they discuss the early years of movement disorder “rock stars”, how the society has changed through their eyes, and impacts it has had on their careers.

Combined habit reversal and acceptance and commitment therapies for tics

Mon, 03 Mar 2025 00:00:00 EST

Dr. Jennifer Eisenhauer joins Dr. Sara Schaefer to discuss her recent article describing a combined therapy approach for adult patient with tics: habit reversal therapy (HRT) + acceptance and commitment therapy (ACT). They further discuss what these therapies are, their effect in tics, what is gratifying about working with patients with tics, and next steps to determine efficacy of this approach. Read the article.

Concomitant pathologies and their clinical impact in multiple system atrophy

Mon, 15 Apr 2024 00:00:00 EST

Dr. Eduardo Fernandez discusses with Dr. Hiroaki Sekiya the surprising findings of his study evaluating the presence of concomitant pathologies and how they impact the disease progression in a large cohort of patients with MSA from the Mayo Clinic brain bank. Read the article

COVID-19 and the Risk of Parkinsonism

Mon, 17 Oct 2022 00:00:00 EST

Dr. Sara Schaefer discusses with Prof. Richard Smeyne how viruses including COVID-19 increase the susceptibility to oxidative stress-induced parkinsonism in mouse models, the historical evidence to support a virus-parkinsonism link, the biological basis for this correlation, and ways it may be prevented.
Journal CME is available until July 29, 2023 Read the article.

CSF proenkephalin as a biomarker for premotor Huntington's disease

Mon, 09 Feb 2026 00:00:00 EST

Dr. Mena Farag joins Dr. Eduardo de Pablo-Fernández to discuss how proenkephalin and other biomarkers can help monitor the earliest stages of Huntington's disease decades before the onset of motor symptoms. Journal CME is available until February 11, 2027
Read the article.

CSF1R-related disorder in China

Tue, 28 May 2024 00:00:00 EST

Dr. Sara Schaefer speaks with Doctors Xiaojun Huang and Jingying Wu about the phenotypic and genotypic spectrum of CSF1R-related disorder in a Chinese population, including unique clinical and radiographic characteristics.
Journal CME is available until May 21, 2025 Read the article.

Current genetic landscape for movement disorders • 2025 MDS Congress

Mon, 20 Oct 2025 00:00:00 EST

The field of genetics often moves quickly, making it a challenge to stay informed. Dr. Gerard Saranza breaks down the current landscape, new discoveries and technologies, and what changes we can expect in the upcoming years.

Current landscape of pediatric movement disorders • 2025 MDS Congress

Mon, 20 Oct 2025 00:00:00 EST

Due to genetic advancements, the pediatric movement disorder field is ever growing. Dr. Shekeeb Mohammad breaks down the current landscape of the field and how adult neurologists can advance their learning.

Current microbiome research for Parkinson's disease • 2025 MDS Congress

Mon, 27 Oct 2025 00:00:00 EST

Prof. Paul Wilmes breaks down his #mdscongress talk discussing the recent studies on the influences of the gut microbiome on PD. He also dives into future goals and what interventions may be beneficial for PD.

Current status of functional neurosurgery • 2025 MDS Congress

Mon, 27 Oct 2025 00:00:00 EST

There have been major breakthroughs in functional neurosurgery. Prof. Jill Ostrem breaks down the latest updates in the field, specifically surrounding adaptive DBS.

Decoding epilepsy dyskinesia syndrome: Clinical clues and genotypic spectrum

Mon, 08 Sep 2025 00:00:00 EST

In this episode, we dive into the world of epilepsy dyskinesia syndrome (EDS) with our guest, Dr. Darius Ebrahimi-Fakhari. Listen as he unpacks the findings from one of the largest multinational studies to date, involving over 600 patients across 25 countries. Read the article.

Deep brain stimulation for GBA-related Parkinson's disease: is it a reasonable option?

Mon, 15 Jan 2024 00:00:00 EST

In this special issue Dr. Avenali and Prof. Valente share the results on a large cohort study investigating the results and risks of deep brain stimulation in people with Parkinson's disease carrying a GBA mutation. Read the article

Deep brain stimulation for Parkinson, beyond motor improvement: Social and occupational outcomes

Tue, 22 Sep 2020 00:00:00 EST

In this interview, Prof. Günther Deuschl highlights the main results of the EARLYSTIM project, focusing on non-motor outcomes, and especially on the effects of DBS on Social and Occupational Functioning in Parkinson's Disease. Read the article

Deep brain stimulation for Parkinson's disease dementia: are we there yet?

Mon, 12 Dec 2022 00:00:00 EST

Dr. Michele Matarazzo interviews Prof. Marjan Jahanshahi on the long term results of the clinical trial of deep brain stimulation of the nucleus basalis of Meynert in people with Parkinson's disease dementia. In the discussion Prof. Jahanshahi shares thoughts on the future directions of the field. Read the article.

Deep brain stimulation in Parkinson's disease with cognitive impairment: real-world evidence

Mon, 01 May 2023 00:00:00 EST

Deep brain stimulation (DBS) has long been considered a risky procedure for people with Parkinson's disease and cognitive impairment. In this interview, Dr. Miocinovic presents real-world data, showing that DBS might be safe and useful in carefully selected patients with moderate cognitive impairment. Read the article.

Defining Parkinson's disease: where we are, where we are headed

Mon, 13 Jan 2025 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Victor Fung, President of the International Parkinson and Movement Disorder Society and lead author of the recent viewpoint published in the Movement Disorders journal. Together, they explore the biological definition and classification of Parkinson's disease, discussing its key insights, future prospects, and the implications of recent advances in the field. Read the article.

Definition and characteristics of early onset PSP: A different disease?

Mon, 14 Oct 2019 00:00:00 EST

In this interview with Dr. Edwin Jabbari, we highlight the results of his study on the definition and genetic and neuropathological characteristics of early onset progressive supranuclear palsy. The full study is available on the September 2019 issue of the Movement Disorders journal. Read the article

Diagnosis of Late-Onset Wilson's Disease

Mon, 15 May 2023 00:00:00 EST

Dr. Christelle Nilles talks with Dr. Hugo Morales Briceno about the clinical presentations of Wilson’s disease patients with onset after 40 years and the challenges of diagnosing patients with atypical neurological manifestations. Read the article.

Differential diagnosis of myoclonus

Mon, 19 May 2025 00:00:00 EST

Prof. Marina de Koning-Tijssen interviews Dr. Christos Ganos on the differential diagnosis of myoclonus. Dr. Ganos explains how he distinguishes between jerky movements based on clinical history and examination, and discusses the differential diagnosis across various parts of the body.

Disease modification and Parkinson’s disease: Clinical trial design and population selection • 2025 MDS Congress

Mon, 20 Oct 2025 00:00:00 EST

There have been nearly 30 years of disease modifying trials for PD, but little success. Prof. Tanya Simuni breaks down clinical trial design for a heterogenous disease like PD and discusses the future goals and importance of a biological definition.

Disentangling the Cognitive Effects of Acute Levodopa in Parkinson's Disease

Mon, 05 Aug 2024 00:00:00 EST

In this episode, Dr. Joseph Seemiller and Dr. Kelly Mills discuss the changes in cognitive performance in the OFF and ON states during an acute levodopa challenge in a large cohort of patients with Parkinson's disease. Their study's findings suggest divergent complex changes in processing speed and executive function. Read the article »

Distinguishing functional from idiopathic dystonia: A novel approach

Mon, 23 Feb 2026 00:00:00 EST

Functional dystonia can closely mimic idiopathic dystonia, and objective physiological markers to support the diagnosis are still limited. In this episode, Dr. Michele Matarazzo speaks with Prof. Roberto Eleopra about a pilot study using poly-EMG during a controlled propofol sedation protocol to help differentiate functional from idiopathic dystonia. They discuss the study’s rationale and design, the key findings, and what this approach could (and could not) add to real-world diagnostic workflows in selected complex cases. Journal CME is available until February 19, 2027
Read the article.

Do social workers play a role in preoperative evaluation for DBS?

Mon, 21 Jul 2025 00:00:00 EST

Nicole Duff and Dr. Amanda Currie discuss the potential role of the social worker in deep brain stimulation (DBS) and the work of Dr. Currie’s team in creating a simple pneumonic that could be used to determine whether a social worker's involvement would be beneficial to DBS patients. They also discuss the clinical implications of this study as well as possible future directions to further outline the role of the social worker in DBS. Read the article.

Do subjective cognitive complaints predict future incident cognitive impairment in people with Parkinson's disease?

Mon, 08 Jul 2024 00:00:00 EST

Dr. Eduardo Fernández and Dr. Daniel Weintraub discuss whether subjective cognitive complaints can predict future incident cognitive impairment and other questions related to early cognitive impairment in people with Parkinson's disease, referencing Dr. Weintraub’s recent article, "Association between subjective cognitive complaints and incident functional impairment in Parkinson's disease" published in Movement Disorders. Read article »

Does glucocerebrosidase activity correlate with disease risk or phenotype severity in Parkinson's disease?

Mon, 11 Apr 2022 00:00:00 EST

A discussion with Dr. Avner Thaler on the findings and implications of a study on the background of importance of GBA mutations and GCase activity in Parkinson's disease. Read the Article.

Dystonia | Congress 2019

Thu, 24 Oct 2019 00:00:00 EST

As part of the MDS Congress 2019 Special Issue, Dr. Sara Schaefer interviews Dr. Hyder Jinnah about notable research in dystonia and activities of the MDS Dystonia Study Group.

Dystonia Series: Beyond “torsion": non-motor features of dystonia

Mon, 06 Feb 2023 00:00:00 EST

In part 2 of the Dystonia Special Series, Dr. Francesca Morgante interviews Dr. Davide Martino on the non-motor features of dystonia.

Dystonia Series: Current and future approaches to treatment of dystonia

Mon, 13 Mar 2023 00:00:00 EST

In part 5 of the Dystonia Special Series, Dr. Francesca Morgante interviews Dr. Jill Ostrem about current and future approaches to treatment of dystonia.

Dystonia Series: Genetic landscape of dystonia

Mon, 20 Feb 2023 00:00:00 EST

In part 3 of the Dystonia Special Series, Dr. Francesca Morgante interviews Prof. Carolyn Sue on the Genetic landscape of dystonia.

Dystonia Series: Pearls on diagnosis and phenomenology

Mon, 23 Jan 2023 00:00:00 EST

In part 1 of the Dystonia Special Series, Dr. Francesca Morgante interviews Dr. Miryam Carecchio on pearls on diagnosis and phenomenology of dystonic syndrome.

Dystonia Series: Unraveling the neural routes of dystonia

Mon, 06 Mar 2023 00:00:00 EST

In part 4 of the Dystonia Special Series, Dr. Francesca Morgante interviews Dr. Anna Sadnicka on the neural roots of dystonia.

Education at the MDS | Congress 2019

Fri, 18 Oct 2019 00:00:00 EST

As part of the MDS Congress 2019 Special Issue, Dr. Sara Schaefer interviews Dr. Ronald Postuma about all of the educational offerings through the MDS, as well as new projects of the MDS Education Committee.

Effects of a probiotic on Parkinson's disease symptoms

Mon, 19 Jan 2026 00:00:00 EST

Dr. Sara Schaefer is joined by Dr. Valentina Leta and Dr. Ray Chaudhuri to discuss their randomized controlled trial on the effects of probiotic use on inflammation, motor, and non-motor symptoms in Parkinson's disease. Journal CME is available until December 18, 2026
Read the article.

Electroconvulsive therapy in movement disorders

Thu, 01 Apr 2021 00:00:00 EST

Dr. Sara Schaefer discusses with Dr. Pedro Garcia Ruiz his recent paper in Movement Disorders Clinical Practice discussing the history and data behind the use of electroconvulsive therapy in Parkinson's disease and other movement disorders. Read the article

Electrophysiology with a focus on cortical myoclonus

Mon, 05 May 2025 00:00:00 EST

Prof. Marina de Koning-Tijssen interviews Professors Anna Latorre and Shabbir Merchant on the topic of electrophysiology, with a focus on cortical myoclonus. Together they discuss the potential applications of electrophysiology for myoclonus in clinical practice. They also explore the complex interface between cortical myoclonus and epilepsy.

Erythrocytic α-synuclein and spreading pathology in Parkinson’s disease

Mon, 26 Feb 2024 00:00:00 EST

Prof. Tiago Outeiro interviews Dr. Jing Zhang on his most recent paper in the Movement Disorder Journal on the erythrocytic alpha synuclein and the gut microbiome. Together they discuss alpha synuclein spreading pathology and the promising future of blood biomarkers for Parkinson’s disease.
Journal CME is available until March 02, 2025 Read the article.

Essential tremor and dystonia: the TITAN study

Mon, 26 Aug 2024 00:00:00 EST

Dr. Sara Schaefer interviews Dr. Roberto Erro on the phenotypic characteristics of essential tremor, essential tremor with soft dystonic signs, and tremor combined with dystonia through analysis of The Italian tremor Network (TITAN) data. Read the article.

Expanded and Independent Spanish Validation of the MDS Non-Motor Rating Scale

Mon, 06 Nov 2023 00:00:00 EST

Dr. Esther Cubo joins Dr. Sarah Lidstone and the MDS Podcast to discuss her recent work on the Spanish validation of the MDS Non-Motor Rating Scale. Together to go over the reasoning for this study, the extensive process of validating this scale and what benefits it will provide to Spanish speaking populations. Read the article
MDS Non-motor Rating Scale

Exploring postural control in functional motor disorders using virtual reality

Mon, 29 Jul 2024 00:00:00 EST

In this episode, Drs. Gandolfi and Tinazzi discuss how virtual reality can be used as a therapeutic tool to modulate attention in patients with functional motor disorder, while measuring postural control. Read the article »

Family history and genetic Alzheimer's risk and ties to Parkinson's disease

Tue, 02 Jan 2024 00:00:00 EST

Dr. Sara Schaefer discusses with Prof. Xiang Gao and Xinming Xu on their study utilizing the UK biobank to explore the risk of Parkinson's disease as it relates to family history of Alzheimer's disease (AD) or dementia and to the polygenic risk score for AD. They further explore the common pathophysiological underpinnings for protein aggregation in the brain. Read the article

Fine tuning DBS in Parkinson's disease. How much can we improve?

Fri, 07 Feb 2020 00:00:00 EST

Dr. Viswas Dayal discusses with Dr. Michele Matarazzo how adjusting the pulse width of deep brain stimulation could impact Parkinson's disease, highlighting the results of the paper he recently published in the Movement Disorders journal. Read the article

Focused ultrasound for cervical dystonia

Mon, 17 Feb 2025 00:00:00 EST

Dr. Shiro Horisawa discusses the latest clinical trial results on MR-guided focused ultrasound pallidothalamic tractotomy for cervical dystonia. He explores the technique's limitations, future prospects, and how it compares to existing therapeutic options. Read the article.

Functional Tic-Like Behaviors: A Common Comorbidity in Patients with Tourette Syndrome

Mon, 24 Jun 2024 00:00:00 EST

Dr. Müller-Vahl joins the podcast to discuss her retrospective study examining the key features in differentiating Tourette syndrome and Functional tic-like behaviors and that comorbidity is far more common than originally thought. Read the article »

Gender differences in DBS decision making

Mon, 07 Apr 2025 00:00:00 EST

Dr. Sara Schaefer discusses with Dr. Michelle Fullard the similarities and differences in how men and women with Parkinson's disease approach the decision of whether or not to undergo deep brain stimulation. Read the article.

Genetic dystonias and understanding molecular pathways • 2024 MDS Congress

Mon, 07 Oct 2024 00:00:00 EST

Prof. Michael Zech takes a dive into his talk on gene discovery in dystonia. He explains how new findings can provide insight into the pathophysiology of dystonia and improve patient care and treatment.

Genetic Highlights in Movement Disorders | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

As genetics become more prominent in patient discussions, Professor Roy Alcalay outlines with Dr. Tiago Outeiro the key implications and opportunities as we enter "a different era of genetic testing."

Genetic testing in deep brain stimulation for Parkinson's disease

Fri, 06 Jun 2025 00:00:00 EST

In this episode, we explore the role of genetics and genetic testing in the decision-making and outcome of deep brain stimulation in Parkinson's disease with two experts in the field: Dr. David Arkadir and Dr. Saar Anis. This interview is also available in the text format within the MDS Scientific Issues: Read the issue

Getting involved in the MDS: a fruitful relationship

Mon, 26 Jun 2023 00:00:00 EST

In this episode, Michele Matarazzo highlights the relevance of our society for the field and its members, with special guest Njideka Okubadejo.

GLP-1 agonists in Parkinson’s disease: New evidence, new questions?

Mon, 31 Mar 2025 00:00:00 EST

In this episode, Dr. Michele Matarazzo interviews Prof. Tom Foltynie about the recently published phase 3 clinical trial of exenatide as a disease-modifying therapy for Parkinson’s disease in The Lancet. While the findings were disappointing, ongoing post-hoc analyses aim to understand the discrepancy with previous phase 2 results and explore how they might shape the future of exenatide and other GLP-1 agonists in neurodegenerative disorders. Read the article.

Hematopoietic stem cell transplantation in CSF1R-related disorder

Mon, 17 Nov 2025 00:00:00 EST

In this episode, Prof. Fanny Mochel discusses the rationale and key findings from a retrospective cohort study of patients with CSF1R-related disorder treated with hematopoietic stem cell transplantation, highlighting the potential of this therapy to achieve both clinical and radiological disease stabilization.
Journal CME is available until September 24, 2026
Read the article.

Heterogeneity of Parkinson's Disease | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

Why is Parkinson's disease heterogeneity important to research. Dr. Connie Marras met with Dr. Eduardo Fernandez to discuss why understanding the heterogeneity of this disease may help with prevention.

Highlights for dystonia • 2025 MDS Congress

Mon, 27 Oct 2025 00:00:00 EST

Prof. Susanne Schneider discusses all things dystonia. Listen as she reviews the revised MDS definition and classification system for dystonia, updates for neurodegeneration with brain iron accumulation, and the exciting future of genetic therapies.

Highlights in ataxia • 2025 MDS Congress

Mon, 27 Oct 2025 00:00:00 EST

Dr. Lauren Jackson discusses recent clinical trials, genetic updates, and interesting research in the field of ataxia.

Highlights in Movement Disorder Education | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

Shifts in the Society and the landscape of the field are set to guide growth in medical education. Dr. Veronica Santini shares insights about this new direction with Dr. Sara Schaefer and our listeners.

Highlights in Multiple System Atrophy Research | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

Multiple system atrophy (MSA) research has its challenges, nonetheless the field is still moving at a rapid pace. Dr. Eduardo Fernandez discusses the MDS Congress highlights for MSA with Dr. Alessandra Fanciulli.

Highlights in Neuroimaging | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

Following a year of impactful neuroimaging papers, Prof. Oury Monchi discusses with Dr. Michele Matarazzo the most promising advances involving machine learning, tracers, and precision in determining imaging processes.

Highlights in Progressive Supranuclear Palsy Research | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

What direction will the field of PSP research go in the years to come? Prof. Gunter Höglinger sits down with Dr. Eduardo Fernandez at the MDS Congress to help answer that very question.

Highlights in Tic and Stereotypies | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

What type of research is needed to help us better understand the phenomenology of stereotypic movements disroders? Dr. Hugo Morales asks Dr. Tammy Hedderly her viewpoint on the uniqueness of these disorders and what questions the field has yet to answer.

Highlights on Parkinson’s Disease | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

Dr. Ron Postuma outlines with Dr. Eduardo de Pablo-Fernández several advances this year he thinks will "revolutionize" Parkinson's disease care, and shifts the field may need to make as a whole to help us reach the next phase of prodromal and personalized treatments.

Highlights on Tic Disorders - Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

As tic cases rise, Dr. Christos Ganos overviews with Dr. Hugo Morales two major treatment advancements, a growing emphasis on neurostimulation research and multidisciplinary care, and progress in the field's largest area of opportunity.

Highlights on Tremor Disorders | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

Dr. Claudia Testa shares with Dr. Sara Schaefer why she believes in the quickly shifting field of tremor, we should be more open-minded about changes in diagnoses over time.

History of Movement Disoders: The influence of videography

Mon, 06 Apr 2026 00:00:00 EST

Dr. Mattia Rosso joins Dr. Sara Schaefer to discuss the historical use of videography in movement disorder clinical practice and education, and how it influenced the evolution of the field. Read the article.

History of Movement Disorders: Huntington's Disease in Venezuela

Mon, 09 Jan 2023 00:00:00 EST

As part of the History of Movement Disorders series, Dr. Sara Schaefer and Dr. David Standaert discuss the research and humanitarian work by Nancy Wexler and team starting in the 1970s in the Venezuelan village of Barranquitas, which has the highest prevalence of Huntington's disease in the world.

History of Movement Disorders: Jean-Martin Charcot

Mon, 12 Jan 2026 00:00:00 EST

In another installment of the ongoing History Series, Dr. Christopher Goetz joins Dr. Sara Schaefer to discuss the legacy of Jean-Martin Charcot within the fields of medicine medicine, neurology, medical education, and movement disorders.

History of Movement Disorders: The Finding of Alpha-Synuclein and Lewy Bodies

Mon, 24 Apr 2023 00:00:00 EST

In this History of Movement Disorders Special Episode, Prof. Tiago Outeiro interviews Prof. Maria Grazia Spillantini about integral work involved in discovering the role alpha-synuclein plays in the development of Lewy bodies. She discusses where the field is now and what questions young researchers should start asking.

History of Movement Disorders: The story of MPTP and parkinsonism

Mon, 23 Jun 2025 00:00:00 EST

In this episode, Prof. Tiago Outeiro interviews Prof. William Langston on the intriguing history of drug addicts manifesting parkinsonism in the 1980s, and how MPTP became a tool compound for modeling certain aspects of Parkinson's disease.

Hot Topic: Focused Ultrasound in Movement Disorders - Blood-Brain Barrier Opening

Mon, 18 Mar 2024 00:00:00 EST

In this Hot Topic episode, Dr. Michele Matarazzo interviews Dr. Nir Lipsman on the Focused Ultrasound-mediated Blood-Brain Barrier Opening, from technical challenges to current evidence and future perspective of this promising technology that could provide a new way to deliver drugs in the brain.

Hot Topic: Focused Ultrasound in Movement Disorders - Brain ablations as a therapeutic tool

Mon, 13 May 2024 00:00:00 EST

In this Hot Topic episode, Dr. Michele Matarazzo interviews Dr. Raul Martinez on the recent evidence and future applications of focused ultrasound-based ablations in movement disorders, such as Parkinson's disease and essential tremors. Discover how this innovative approach is improving patient care and what it could mean for the future of medical treatment.

Hot Topic: Focused Ultrasound in Movement Disorders - Neuromodulation

Mon, 04 Mar 2024 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Robert Chen about the rapidly expanding applications of focused ultrasound-based neuromodulation in neurology, particularly in movement disorders, from tremor to Parkinson's disease. Tune in to uncover the future and potential of non-invasive neurotherapies that are setting new standards in research and patient care.

Hot topic: GP2 and underrepresented populations

Mon, 23 Oct 2023 00:00:00 EST

The Global Parkinson's Genetics Program (GP2) is a project designed to understand the architecture of Parkinson's disease (PD). Dr. Sarah Camargos sits down with Dr. Andrew Singleton to discuss GP2 and its initiative to increase our global understanding of PD and in doing so, better understand the genetic landscape of underrepresented populations.

Hot Topic: Integrating palliative care into routine care for patients with movement disorders

Mon, 22 Dec 2025 00:00:00 EST

Dr. Sarah Camargos continues her conversation on palliative in movement disorders by interviewing Mr. Victor McConvey. Together they discuss the current state of palliative care in movement disorders including current barriers, challenges, and future goals.

Hot Topic: Limitations of phenomenology in functional movement disorders: what can we learn?

Mon, 17 Jun 2024 00:00:00 EST

In this Hot Topic episode, Dr. Sarah Lidstone moderates a discussion with Dr. Mark Hallett and Prof. Mark Edwards on the limitations of phenomenology in movement disorders. Drawn from a recent viewpoint by Prof. Edwards and using functional movement disorder as an example, they discuss the benefits and drawbacks of a phenotype equaling disease paradigm, the voluntary vs. involuntary movement disorder, and what we can learn from functional movement disorders.

Hot Topic: Normal pressure hydrocephalus - Assessments for intervention, outcomes, and future directions

Tue, 02 Sep 2025 00:00:00 EST

In the third and final episode of the normal pressure hydrocephalus (NPH) Hot Topic series, Dr. Sara Schaefer speaks with Dr. Joachim Krauss about the assessment of patients with NPH for neurosurgical intervention, outcomes data, and his vision for the future of NPH research and clinical care.

Hot Topic: Normal pressure hydrocephalus - Clinical aspects and differential diagnosis

Mon, 18 Aug 2025 00:00:00 EST

In this first episode of the Hot Topic series on normal pressure hydrocephalus, Dr. Sara Schaefer discusses with Dr. Mats Tullberg the symptoms of NPH, examination techniques and pearls, imaging findings, and the differential diagnosis.

Hot Topic: Normal pressure hydrocephalus - Pathophysiology and controversies

Mon, 25 Aug 2025 00:00:00 EST

In this second episode of the Hot Topic series on normal pressure hydrocephalus, Dr. Sara Schaefer discusses with Dr. Alfonso Fasano the pathophysiological theories behind NPH, co-pathology in this population, and controversies surrounding the disease.

Hot Topic: Palliative care in movement disorders

Mon, 24 Nov 2025 00:00:00 EST

In this Hot Topic episode, Dr. Sarah Camargos talks with Prof. Janis Miyasaki about the meaning and benefits of palliative care and how it improves quality of care in movement disorders.

Hot Topic: Pesticides and Parkinson's Disease 1

Tue, 03 Sep 2024 00:00:00 EST

Prof. Daniela Berg joins Prof. Tiago Outeiro in this first Hot Topic episode focusing on pesticides and Parkinson’s disease (PD). Together they discuss the rise of PD, the impact of pesticides, and what should be done to safeguard people from potential harm.

Hot Topic: Pesticides and Parkinson's Disease 2

Mon, 09 Sep 2024 00:00:00 EST

For this Hot Topic episode, Prof. Tiago Outeiro talks with Dr. Briana de Miranda about the basic science behind the relationship between pesticides and Parkinson's disease. Together they discuss the possible mechanistic action of these products and how dopaminergic neurons are more susceptible.

Hot Topic: Subcutaneous levodopa infusion

Mon, 10 Feb 2025 00:00:00 EST

Dr. Hugo Morales Briceno interviews Prof. Ray Chaudhuri to discuss the real world-use of levodopa subcutaneous infusion in patients with Parkinson's disease.

Hot topic: The gut microbiome in Parkinson's

Mon, 17 Apr 2023 00:00:00 EST

In this special Hot Topics episode, Dr. Filip Scheperjans discusses what we know and what we don't yet know about the gut microbiome in Parkinson's disease, theories of influencing pathways within the gut-brain axis, and future directions for exploring and altering the gut microbiome in this patient population to impact disease.

Hot Topic: Tissue-based biomarkers in Parkinson's disease

Mon, 20 Nov 2023 00:00:00 EST

For this Hot Topics episode, Dr. Eduardo Fernandez sits down with Dr. Thomas Beach to discuss the advances and challenges ahead in tissue biomarkers for Parkinson's disease, including colon, salivary gland and skin biopsies.

How not to conduct a peer review: Fatal, avoidable errors.

Mon, 27 Jun 2022 00:00:00 EST

In this episode of the special series focused on the peer review process, Dr. Shweta Prasad speaks with Prof. Jose Obeso to discuss some points on how NOT to conduct a peer review.

How to manage Parkinson's disease and related disorders, and is there a link between COVID and PD?

Mon, 18 May 2020 00:00:00 EST

Dr. Michele Matarazzo interviews Prof. Angelo Antonini on the effect of the COVID-19 pandemic on Parkinson's disease and other movement disorders patients and how to manage them. And also, what is the evidence of a link between COVID-19 and Parkinson's disease? Read the article

How to review an original scientific article

Mon, 02 May 2022 00:00:00 EST

For this episode of our special series focused on the peer review process, Dr. Alana Kirby speaks with Dr. Tony Lang about how to approach reviewing an original scientific article.

Huntington's disease | Congress 2019

Wed, 23 Oct 2019 00:00:00 EST

As part of the MDS Congress 2019 Special Issue, Dr. Schaefer and Dr. Sarah Tabrizi discuss the evolving research in disease-modifying therapies for Huntington's Disease, and what may come next. Read the article

Idiopathic Normal Pressure Hydrocephalus: Critical Review of Objective Findings

Mon, 16 Jan 2023 00:00:00 EST

Prof Martino points out the existent literature concerning the objective findings in the 3 cardinal domains of idiopathic normal pressure hydrocephalus. Read the article.

Immune, metabolic and tau markers in blood cells in progressive supranuclear palsy

Mon, 24 Feb 2025 00:00:00 EST

Dr. Eduardo de Pablo-Fernández and Dr Tommaso Schirinzi discuss the results of his study evaluating markers of immune response, metabolism, inflammatory regulation and tau levels in blood cells in patients with progressive supranuclear palsy (PSP). They also discuss how these results contribute to the growing evidence of neuroinflammation contributing to the pathogenesis of PSP.
Journal CME is available until October 21, 2025 Read the article.

Implanted system for orthostatic hypotension in multiple-system atrophy

Mon, 22 Aug 2022 00:00:00 EST

Dr. Sara Schaefer speaks with Drs. Gregoire Courtine and Jocelyne Bloch about the use of an implanted spinal cord stimulator for the treatment of orthostatic hypotension in multiple-system atrophy. Read the article.

Infectious agents as drivers of synucleinopathies?

Mon, 25 Apr 2022 00:00:00 EST

Dr. Tiago Outeiro interviews Dr. Morgane Linard about the recently published article, "Infectious Agents as Potential Drivers of α-Synucleinopathies." Read the Article.
Journal CME will be available for this article until March 18, 2023.

Inflammation is an early feature of Parkinson's disease

Mon, 29 May 2023 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Talene Yacoubian on an article recently published on the Movement disorders journal that reveals increased inflammatory markers in recently diagnosed patients with Parkinson's disease without medication, suggesting the important role of inflammation from the early stages of the disease. Furthermore, inflammatory biomarkers are related to cognition.
Journal CME is available until May 22, 2024 Read the article.

Integrated therapy for functional movement disorders

Fri, 21 Feb 2020 00:00:00 EST

Dr. Sara Schaefer discusses with Dr. Sarah Lidstone her recent paper in Movement Disorders Clinical Practice about a novel, multidisciplinary therapeutic intervention for functional movement disorders patients. Read the article

International Parkinson and Movement Disorder Society Mission and Structure

Mon, 08 May 2023 00:00:00 EST

Sara Schaefer discusses the history, inner workings, and vision of the International Parkinson and Movement Disorder Society with current MDS President Francisco Cardoso.

Interview with Dr. Jon Stoessl on Preprints in the COVID-Era

Sun, 20 Sep 2020 00:00:00 EST

Preprint articles of scientific results have been thrust into the spotlight due to the desire for rapid results pertaining to COVID-19. Here, we dive into the trend with Movement Disorders’ editor, Dr. Jon Stoessl. Read the article

Interview with the president on the MDS activities during the COVID crisis

Tue, 26 May 2020 00:00:00 EST

In this interview the president of the MDS, Prof. Claudia Trenkwalder shares the main changes and strategies that the MDS is implementing to adapt to the COVID-19 pandemic, including the replacement of the International MDS congress with a virtual meeting.

Intraventricular infusion of anaerobic dopamine

Mon, 12 May 2025 00:00:00 EST

Dr. Hugo Morales Briceno interviews Prof. David Devos from the University of Lille, France, about the results of the phase 1/2 clinical trial using intracerebroventricular anaerobic dopamine in Parkinson’s disease with L-dopa-related complications. Read the article.

Introduction and functional movement disorders | Congress 2019

Fri, 18 Oct 2019 00:00:00 EST

Did you miss the MDS Congress in Nice, or do you just want an overview of highlights from the International Congress as well as a look forward at new ventures? Dr. Schaefer introduces the MDS Congress 2019 special issue, which features interviews with experts in various fields of movement disorders at the MDS Congress 2019. In this first issue, Dr. Sara Schaefer interviews Dr. Kathrin LaFaver about notable research in functional movement disorders, activities of the MDS Functional Movement Disorders Study Group, and more.

Iron imaging of substantia nigra in Parkinson's disease: A possible biomarker?

Tue, 06 Aug 2019 00:00:00 EST

Dr. Niels Bergsland discusses with Dr. Michele Matarazzo the results of the article he recently published in the Movement Disorders journal on longitudinal iron imaging in the substantia nigra in PD and in its different regions. Read the article

Is benign hereditary chorea really benign?

Wed, 20 Feb 2019 00:00:00 EST

Dr. Mered Parnes discusses with Dr. Sara Schaefer his article on benign hereditary chorea recently published in the January 2019 issue of the Movement Disorders Clinical Practice. Read the article

Is levodopa disease modifying? Long-term LEAP study follow-up

Mon, 22 Jul 2024 00:00:00 EST

Prof. Rob de Bie joins Dr. Sara Schaefer to discuss the 5-year follow up extension to the Levodopa in Early Parkinson's disease (LEAP) study, including the results and indications for practice.
Journal CME is available until July 01, 2025 Read the article.

Is propriospinal myoclonus a functional movement disorder?

Mon, 02 Jun 2025 00:00:00 EST

In this episode, Prof. Marina de Koning-Tijssen interviews Prof. Mark Edwards. Together they delve into both the clinical and electrophysiological aspects of propriospinal myoclonus, and explore the distinguishing features and current treatment options for functional movement disorders.

Junior Awardee - SAA development for the differentiation of progressive supranuclear palsy and Parkinson's disease | Congress 2024

Mon, 23 Sep 2024 00:00:00 EST

Dr. Edwin Jabbari, a 2024 MDS Junior Award Winner, joins the MDS Podcast to share the results of his award-winning work on the development of a 4-repeat tau SAA and what led him to this work. He also shares helpful tips for other junior researchers.

Junior Awardee - Understanding the optimal brain fingerprint to improve DBS outcomes in Parkinson's disease | Congress 2024

Mon, 23 Sep 2024 00:00:00 EST

Dr. Bahne Bahners, a 2024 MDS Junior Award Winner, discusses the path that led him to his chosen research topic and award. He shares the results of this novel investigation that studies the electrophysiological fingerprint of STN DBS clinical outcomes using local field potential and magnetoencephalography recordings.

Junior Awardee: Identifying a subthalamic nucleus cell subtype responsible for motor benefit in a Parkinsonian mouse model | Congress 2025

Mon, 29 Sep 2025 00:00:00 EST

Dr. Mitra Afshari chats with Dr. Jung Hawn Shin, one of this year’s MDS Congress Junior Awardees. Together they discuss his career path and what lead him to studying, and ultimately deciphering specific neuronal cell-types within the subthalamic nucleus (STN) that could be responsible for anti-parkinsonian motor benefits, and potentially non-motor side effects, of stimulation using optogenetic technology in Parkinsonian mice.

Junior Awardee: Mitochondrial and oligodendrocytic processes in MSA | Congress 2025

Mon, 29 Sep 2025 00:00:00 EST

Dr. Eduardo de Pablo-Fernández interviews one of the 2025 Junior Awardees, Dr. Lydia Chougar about her work combining neuroimaging with transcriptomics and PET maps to elucidate the biological underpinnings of structural abnormalities in multiple system atrophy.

Late-stage Parkinsonism: Do we know enough?

Wed, 08 Jul 2020 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Anette Schrag about the recently published article on late-stage parkinsonism and related neuropsychiatric complications. Why is it important? And are we doing enough to help patients at this stage? Read the article

Lixisenatide in Parkinson's: A Diabetes Drug to Slow Disease Progression?

Mon, 01 Jul 2024 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Olivier Rascol on the results of the clinical trial recently published in the New England Journal of Medicine. Tune in to learn about the mechanisms of action and potential of lixisenatide and other GLP-1 receptor agonists in impacting the progression of Parkinson's disease. Read the article »

Local fields potentials can help DBS programming in Parkinson's disease in clinical practice

Mon, 29 Jan 2024 00:00:00 EST

Dr. Michele Matarazzo interviews Prof. Andrea Kühn on her recently published article showing the potential of local fields potentials to help the programming of deep brain stimulation in patients with Parkinson's disease. Read the article

Long-term follow up of GPi-DBS in pediatric non-degenerative dystonia

Mon, 19 Aug 2024 00:00:00 EST

Dr. Sarah Camargos interviews Dr. Giovanna Zorzi on the outcomes of a cohort of non-degenerative pediatric patients with idiopathic and genetic dystonia who were submitted to GPi-DBS and compares these outcomes with a meta-analysis of the literature.
Journal CME is available until July 24, 2025 Read the article.

Long-Term Follow-Up of Patients with Mass Social Media-Induced Illness Presenting with Functional Tic-like Behaviors

Mon, 09 Mar 2026 00:00:00 EST

In this episode, Dr. Kirsten Müller-Vahl explores one of the first long-term follow-up studies of mass social media–induced functional tic-like behaviors (MSMI-FTLB). She discusses what their findings mean for clinical counseling, why early diagnosis appears to improve outcomes, how factors such as psychiatric comorbidity and secondary gain influence recovery. She also examines the surprising finding that reduced screen time did not significantly affect prognosis and what this suggests about social media as a trigger versus a maintaining factor. Read the article.

Long-term outcomes of focused ultrasound in essential tremor

Thu, 06 Jun 2019 00:00:00 EST

Dr. Jin Woo Chang shares the results of 4-year follow-up of MR-guided focused ultrasound thalamotomy in essential tremor. In his article, recently published in the Movement Disorders journal, he analyzes whether the efficacy of this procedure is sustained over time. Read the article

Machine learning for drug repurposing: A novel approach to find new treatments for Parkinson's disease

Mon, 27 Feb 2023 00:00:00 EST

Dr. Matarazzo interviews Émeline Courtois about the recently published article on machine learning approach to discover marketed drugs that could have an impact on the development of Parkinson's disease. Interestingly, furosemide and adrenergic drugs showed a potential protective effect in this very large cohort.
Journal CME is available until January 19, 2024 Read the article.

MDCP Research Article of the Year: The Role of Levodopa Challenge in Predicting the Outcome of STN DBS

Fri, 27 Sep 2024 00:00:00 EST

Award Replay: Dr. Eduardo Fernandez interviews Professor Günther Deuschl and Dr. Robin Wolke on their article on the challenges levodopa poses when predicting the outcome of subthalamic deep brain stimulation — which was recently named the Movement Disorders Clinical Practice journal Research Article of the Year. Read the article

MDCP Research Article of the Year: Are hyposmia and REM sleep behavior disorder reliable indicators of Lewy body pathology?

Mon, 22 Sep 2025 03:24:00 EST

MDCP Review Article of the Year: Alpha-Synuclein Seed Amplification Assays in CSF

Mon, 02 Oct 2023 00:00:00 EST

Dr. Sara Schaefer speaks with Dr. Beatrice Heim, author of the MDCP Review Article of the Year 2023, about alpha-synuclein seed amplification assays of the CSF and their use in the diagnosis of synucleinopathies. Read the article

MDCP Review of the Year: Why should subacute sclerosing panencephalitis be on our radar?

Mon, 22 Sep 2025 00:00:00 EST

This year’s MDCP Review Article of the Year covers the spectrum of movement disorders associated with subacute sclerosing panencephalitis (SSPE). Dr. Sarah Camargos interviews Dr. Charulata Sankhla on her team’s findings and why she believes movement disorder specialists should be aware of this measle-associated complication. Read the article.

MDJ Research Article of the Year: Harmonizing genetic testing for Parkinson's disease

Mon, 28 Oct 2024 00:00:00 EST

Prof. Alessio Di Fonzo shares the results of his award winning, multi-center work examining genetic data from people with early-onset PD in hopes of highlighting the difficulties in interpreting genetic variants emerging from NGS-multigene panels. Read the article.

MDJ Research Article of the Year: Microglial activation in isolated REM sleep behavior disorder

Mon, 03 Nov 2025 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Victor Hvingelby, the recipient of this year’s MDJ Research Article of the Year award. Together they discuss the use of PET tracers to assess microglial activation in isolated REM sleep behavior disorder and how these tools can better define prodromal Parkinson’s disease.

MDJ Review Article of the Year Award: How does DBS change the course of Parkinson's?

Mon, 02 Oct 2023 00:00:00 EST

Dr. Poewe and Dr. Mahlknecht discuss the details of their Review Article of the Year on what we know about how DBS in Parkinson's disease alters symptoms, disability, survival, and more in this special episode. Read the article

MDJ Review Article of the Year: Subjective Cognitive Complaints in Parkinson's Disease

Fri, 27 Sep 2024 00:00:00 EST

Dr. Sara Schaefer interviews Dr. Jennifer Goldman about her systematic review and meta-analysis on subjective cognitive complaints in Parkinson's disease, including the prevalence, epidemiology, and correlation with objective cognitive findings and neuropsychiatric disease. The article was recently named the Movement Disorders journal Review Article of the Year.

MDJ Review of the Year: "Deep Genotyping" - What third-generation sequencing can teach us

Mon, 03 Nov 2025 00:00:00 EST

Dr. Sarah Camargos interviews Dr. Guillaume Cogan and Prof. Alexis Brice, the corresponding authors of the article selected as the Movement Disorders Review of the Year. Listen as their conversation dives into the new sequencing technologies, and the broader diagnosis they bring to the field.

MDS Criteria for the diagnosis of Multiple System Atrophy: New features and implications

Mon, 18 Jul 2022 00:00:00 EST

Dr. Eduardo de Pablo-Fernández interviews Dr. Iva Stankovic and Prof. Gregor Wenning on the newly published MDS Criteria for the Diagnosis of Multiple System Atrophy. Read the article.
Journal CME will be available for this article until June 17, 2023.

MDS PSP criteria in practice: From clinical phenotyping to pathological diagnosis

Fri, 30 Aug 2019 00:00:00 EST

Dr. Farwa Ali discusses with Dr. Sara Schaefer the results of her study on the use of the MDS criteria for PSP with the MAX rules and their clinical implications, as well as the challenges of the phenotype variability of this disease in clinical practice and research. Read the article

Measuring gait through brain metabolism in Parkinson's disease: How it can help understanding and treating gait disorders

Mon, 08 Aug 2022 00:00:00 EST

Dr. Hilmar Sigurdsson shares the results of an FDG PET study that found 2 distinct patterns of brain metabolism related to gait disfunction in PD, suggesting that this objective measure could help better understand the neural basis of gait disorders and could also be used to predict gait involvement in clinical practice and as outcome measure in clinical trials. Read the article.

Mitochondrial DNA copy number: A potential biomarker for Parkinson's disease progression

Mon, 24 Mar 2025 00:00:00 EST

Prof. Sarah Camargos interviews Prof. Sun Ju Chung about his recent paper in the Movement Disorders Journal investigating diagnostic and prognostic capabilities of measuring blood mitochondrial DNA copy number (mtDNA-CN) for Parkinson’s disease.
Journal CME is available until March 3, 2026 Read the article.

Mortality in Parkinson's disease: findings from a nationwide study from Finland

Mon, 12 Feb 2024 00:00:00 EST

Dr. Jussi Sipilä joins Dr. Eduardo de Pablo-Fernandez to discuss the interesting findings of the article on mortality rate in Parkinson's disease using nationwide data from multiple health registries in Finland. Read the article

Motor rehabilitation for Parkinson’s disease • 2025 MDS Congress

Mon, 20 Oct 2025 00:00:00 EST

Rehabilitation for movement disorders, like PD, has become increasingly prevalent for patient care. Prof. Alice Nieuwboer discusses how technology has shaped the field, how neurologists can support patient exercise, and what future updates she looks forward to.

Myoclonus dystonia: Motor & non-motor symptoms and the effect of DBS

Mon, 16 Jun 2025 00:00:00 EST

Prof. Marina de Koning-Tijssen interviews Prof. Kathryn Peall about her expertise on a topic that lies at the heart of her work: Myoclonus dystonia. We’ll hear her insights on both the motor and non-motor challenges faced by patients, and how deep brain stimulation is reshaping treatment possibilities.

Myoclonus new classification & treatment

Mon, 21 Apr 2025 00:00:00 EST

Prof. Marina de Koning-Tijssen interviews Prof. John Caviness on the topic of myoclonus, focusing on its new classification and treatment. They discuss the long-awaited recently published classification of myoclonus and explore the latest treatment options.

Neurofilament light chain in Parkinson's disease

Fri, 20 Nov 2020 00:00:00 EST

Dr. Brit Mollenhauer discusses the recent advances in the use of neurofilament light chain for the diagnosis and follow up of Parkinson's disease and related disorders, highlighting the results of a recent longitudinal study. Read the article

Neuroimaging in movement disorders | Congress 2019

Thu, 24 Oct 2019 00:00:00 EST

As part of the MDS Congress 2019 Special Issue, Dr. Sara Schaefer interviews Dr. Antonio Strafella about the emerging research in neuroimaging in movement disorders and plans to establish a centralized database for neuroimaging in atypical parkinsonisms.

Neuroinflammation in Parkinson's disease

Mon, 04 Jan 2021 00:00:00 EST

Dr. Mcihele Matarazzo interviews Dr. David Standaert about the review article he recently published on neuroinflammation in Parkinson's disease, including the main evidence of its role on the pathogenesis of the disease and how understanding it better may help us discovering new therapeutic targets. Read the article

Neuropsychiatric features of punding and hobbyism in Parkinson's disease

Tue, 15 Feb 2022 00:00:00 EST

Dr. Hugo Morales discusses "Neuropsychiatric Features of Punding and Hobbyism in Parkinson’s Disease," by Dr. Pedro Barbosa et al., from Movement Disorders Clinical Practice. Read the article.

Neurotrophic factors to restore dopaminergic terminals in Parkinson's disease: A viral vector-delivered genetic therapy

Mon, 28 Jul 2025 00:01:00 EST

Could gene therapy with neurotrophic factors help restore dopaminergic terminals in Parkinson’s disease? Dr. Michele Matarazzo speaks with Dr. Amber Van Laar about her team’s Phase 1b trial of AAV2–GDNF gene therapy delivered directly to the putamen. They discuss the preclinical evidence for GDNF, how advanced delivery techniques and higher putamen coverage may overcome past challenges, and the encouraging early results in moderate Parkinson’s. The conversation also explores lessons from previous trials, safety outcomes, and the path forward.
Journal CME is available until June 25, 2026
Read the article.

Neurovascular health and Lewy body disorders, where is the connection?

Mon, 12 Aug 2024 00:00:00 EST

Studies have shown a close interplay between the cerebrovascular system and neurodegeneration. But what is the current evidence, and how can it help us better understand the pathophysiology of Lewy body disorders and potentially change their course? In this episode, Dr. Michele Matarazzo interviews Prof. Sephira Ryman about a recently published review article that explores the complexities of this relationship.
Journal CME is available until August 21, 2025 Read the article.

New genes and technologies for movement disorder genetics • 2024 MDS Congress

Mon, 07 Oct 2024 00:00:00 EST

Dr. Kishore Kumar shares the new genes associated with Parkinson's disease, dystonia, and ataxia. He also shares how new technologies, like long read sequencing, can assist in finding epigenetic changes.

New loci for Parkinson disease is identified in Latin America cohorts

Mon, 04 Sep 2023 00:00:00 EST

Dr. Sarah Camargos interviews Dr. Thiago Leal and Dr. Ignacio Mata about the need of genetic studies on underrepresented populations and the technical challenges they faced when alayzing admixture ancestries and X chromosome. Read the article

New technologies in movement disorders | Congress 2019

Wed, 06 Nov 2019 00:00:00 EST

As part of the MDS Congress 2019 Special Issue, Dr. Matarazzo interviews Dr. Alberto Espay about technology in movement disorders, highlighting recent advances and the goal of the MDS to create a platform that will combine technology-based data and e-diaries.

Nosology and Cut-Off Values for Axial Postural Abnormalities in Parkinsonism

Mon, 31 Oct 2022 00:00:00 EST

Members of the task force for Axial Postural Abnormalities in Parkinsonism, Prof. Tinazzi, Dr. Geroin and Dr. Artusi, discuss new nosology and cut-off values. Read the article.

Off-State Dyskinesias after GDNF Infusion in Parkinson's Disease

Mon, 30 Jan 2023 00:00:00 EST

Sara Schaefer speaks to Alan Whone of the University of Bristol on his retrospective analysis of off-state dyskinesias in Parkinson's disease patients who received serial infusions of GDNF into the putamen. Read the article.

Overview and core components of the peer review process

Mon, 07 Mar 2022 00:00:00 EST

For the first episode of the special series focused on the peer review process, Dr. Daniel Di Luca speaks with Dr. Christopher Goetz about the importance and most important aspects of a peer review.

Pallidotomy for Focal and Hemidystonia

Mon, 11 Mar 2024 00:00:00 EST

Prof. Paresh Doshi discusses with Dr. Sara Schaefer the short- and long-term outcomes of unilateral radiofrequency pallidotomy in focal and hemidystonia patients in this single-blind cohort study published in Movement Disorders Clinical Practice. Read the article

Parkin Maintains Robust Pacemaking in Human iPSC-derived A9 Dopaminergic Neurons

Fri, 07 Jul 2023 00:00:00 EST

In this episode, we interviewed Prof. Jian Feng about his most recent paper covering the role of parkin mutations in human A9 dopaminergic neurons and role they play in locomotor activities of early-onset PD.
Journal CME is available until July 20, 2024 Read the article.

Parkinsonian syndromes and Parkinson's subtypes: Will a single neuroimaging modality ever be enough?

Mon, 01 Feb 2021 00:00:00 EST

Dr. Sara Schaefer speaks with Dr. Nicola Pavese about the imaging modalities currently in use and emerging to differentiate parkinsonian syndromes and Parkinson's subtypes, and how imaging helps us to understand, study, and treat these conditions. Read the article

Parkinsonian syndromes and Parkinson's subtypes: Will a single neuroimaging modality ever be enough?

Wed, 01 Jan 2020 00:00:00 EST

Parkinson's disease and Lewy body disorders | Congress 2019

Wed, 06 Nov 2019 00:00:00 EST

As part of the MDS Congress 2019 Special Issue, Dr. Matarazzo interviews Dr. K. Ray Chaudhuri about news in Parkinson’s disease and Lewy body dementia, including new treatments, scales and other advances in early and late-stage PD. Read the article

Parkinson's disease and type 2 diabetes: Clinical impact and therapeutic implications

Mon, 05 Sep 2022 00:00:00 EST

Dr. Eduardo de Pablo-Fernández speaks with Dr. Dilan Athauda about his recent paper, "The impact of type 2 diabetes in Parkinson's disease" recently published in Movement Disorders. They discuss the clinical impact of type 2 diabetes in the phenotype and disease progression and the therapeutic implications of this association. Read the article.

Parkinson's disease medications during hospitalization

Thu, 30 Jun 2022 00:00:00 EST

Dr. Sara Schaefer and Dr. Georgia Richard discuss the breakdown in medication prescribing and administration in hospitalized Parkinson's patients, and potential strategies for improvement. Read the article.

Past, present, future: An interview with MDS President • 2024 MDS Congress

Mon, 07 Oct 2024 00:00:00 EST

Dr. Victor Fung sat down with Dr. Michele Matarazzo at the #mdscongress to reflect on the advice from his predecessors and how that is helping him achieve his goals as MDS President.

Pathological Validation of 2022 MSA Criteria

Mon, 10 Apr 2023 00:00:00 EST

Sara Schaefer discusses with Dr. Eduardo de Pablo-Fernandez his recent paper in Movement Disorders providing retrospective pathological validation of the 2022 MDS MSA Criteria using specimens from the Queens Square Brain Bank. Read the article.

Patient vs. care partner assessment of cognitive disability in Parkinson's: Who's more accurate?

Fri, 28 Jun 2019 00:00:00 EST

Benjamin Deck discusses with Dr. Schaefer the article he recently published in the Movement Disorders Clinical Practice on the patient vs. care partner assessment of cognition in Parkinson's disease. Read the article

Peer review: Past, present and future

Mon, 25 Jul 2022 00:00:00 EST

In the last episode focused on peer reviews, Dr. Michael Okun discusses historical perspectives and future directions of the peer review process.

Perampanel may reduce alpha-synuclein transmission in Parkinson's disease. A possible therapeutic target?

Mon, 18 Oct 2021 00:00:00 EST

Dr. Michele Matarazzo speaks with Prof. Ryosuke Takahashi about the results of his recent study that shows how this anti-epileptic drug may inhibit the transmission of alpha synuclein in PD. While this was tested in animal models, future clinical trials are warranted to test the effects on PD progression. Read the article

Perry Disease

Fri, 04 Aug 2023 00:00:00 EST

Dr. Wszolek shares with Dr. Schaefer his extensive knowledge about the clinical, genetic, and pathological findings in Perry disease, a rare and likely underdiagnosed parkinsonian condition. Read the article.

Pesticide exposure and dream-enacting behavior

Mon, 06 Jun 2022 00:00:00 EST

Dr. Hugo Morales interviews Dr. Chen Honglei about his most recent paper "High Pesticide Exposure Events and Dream-Enacting Behaviors Among US Farmers" published in the Movement Disorders journal. Read the article.
Journal CME will be available for this article until May 20, 2023.

Pleiotropy in Parkinson´s disease and Cancer: Is there an association between these entities?

Mon, 24 Jul 2023 00:00:00 EST

In this episode, Dr. Pierre-Emmanuel Sugier discusses the epidemiological associations between PD and cancers. While investigating several European GWAS databases, his group raised the conundrum whether cancer and Parkinson's disease share common risk factors. Read the article.

Practicing medicine in time of pandemic and future of Movement Disorders medical practice

Tue, 26 May 2020 00:00:00 EST

Dr. Michele Matarazzo interviews Prof. Roy Alcalay on the effects that the COVID-19 pandemic is having on the clinical activity and how it is changing the way we see patients. Will telemedicine be an integrating part of our clinical practice?

Pregnancy and Parkinson’s disease: Navigating care before, during, and after

Mon, 26 Jan 2026 00:00:00 EST

In this episode, Dr. Alexander Lehn explores the clinical management of Parkinson’s disease across the reproductive journey; before conception, during pregnancy, and in the postpartum period. He shares the current evidence, practical challenges, medication safety considerations, and multidisciplinary decision-making. The conversation highlights gaps in data, real-world clinical strategies, and key counseling points to support optimal outcomes for both the parent and child. Read the article.

Presidential Lecture Awardee - Insight into clinical phenotyping and the role of AI | Congress 2024

Mon, 16 Sep 2024 00:00:00 EST

Dr. Marina de Koning Tijssen, the 2024 Stanley Fahn Presidential Lecture Award Winner, discusses her career history and how much she learned just by talking to patients. She also shares her views on the role of AI in the clinic and what legacy she hopes to leave for future movement disorders specialists.

Presidential Lecture Awardee - The importance of alpha-synuclein research | Congress 2024

Mon, 16 Sep 2024 00:00:00 EST

Dr. Virginia Lee, the 2024 C. David Marsden Presidential Lecture Award Winner, recounts her career and what events lead her to study neurodegenerative disease. She also shares her insight into the importance of alpha synuclein research and advice for aspiring researchers.

Presidential Lecture Awardee: A career observing the brain in action | Congress 2025

Mon, 15 Sep 2025 00:00:00 EST

Dr. Jon Stoessl looks back on his distinguished career in neuroimaging, highlighting the discoveries that have advanced our understanding of Parkinson’s disease and related conditions. In this conversation, he reflects on the evolution of imaging technologies, the challenges of interpreting complex data, and the lessons learned throughout his journey. His recognition with the David Marsden Lecture Award underscores the lasting impact of his contributions to the field.

Presidential Lecture Awardee: Holistic conceptualization of patients with chronic illness | Congress 2025

Mon, 15 Sep 2025 00:00:00 EST

Prof. Mark Edwards, the awardee for the 2025 Stanley Fahn Lecture Award, discusses his work and interest in the neurology-psychiatry continuum as it relates to the care of patients with chronic neurological diseases, including functional neurological disorders.

Presidential Perspective | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

MDS President Francisco Cardoso shares with Dr. Sara Schaefer his important takeaways from his presidential term and his hopes for the future.

Prime editing - A future therapy for cortical myoclonus?

Mon, 30 Jun 2025 00:00:00 EST

Prof. Marina de Koning-Tijssen interviews Prof. Sabine Fuchs on the potential of prime editing as a future therapy for cortical myoclonus. This exciting new development holds promise for the treatment of rare genetic disorders such as GOSR2. In the interview, Prof. Fuchs provides valuable insights into the science and potential applications of this groundbreaking technique.

Promoting diversity and access to care and education - MDS 40th Anniversary

Mon, 01 Dec 2025 00:00:00 EST

To celebrate the 40th Anniversay of the MDS, Dr. Sara Schaefer sits down with two key leaders of the MDS African Regional section, Dr. Njideka Okubadejo and Dr. Jonathan Carr. Together they discuss their experiences within MDS and what makes them proud to be long-standing members.

Randomized controlled trial of exercise on objective and subjective sleep in Parkinson's disease

Wed, 14 Oct 2020 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Amy Amara, the first author of the article awarded as "2020 Research Article from Movement Disorders" on the effects of exercise on sleep in Parkinson's disease. Read the article

Rasagiline in PD: Does it change disease progression? And how do we measure it?

Mon, 09 May 2022 00:00:00 EST

A recent trial showed no benefit of 1mg rasagiline versus placebo on 1-year progression in an early Parkinson's disease cohort. The investigators used a novel method to track disease progression with MRI, apart from usual clinical standards. Dr. David Vaillancourt shares the results of this trial recently published in the Movement Disorders Journal. Read the article.

Rethinking Parkinson’s: The Somato-Cognitive Action Network (SCAN) hypothesis

Mon, 23 Mar 2026 00:00:00 EST

Dr. Michele Matarazzo interviews Prof. Hesheng Liu about his recent Nature paper proposing a major conceptual shift: Parkinson’s disease as a somato-cognitive action network (SCAN) disorder. Together they discuss how a large multimodal dataset suggests a characteristic pattern of hyperconnectivity between SCAN cortical areas and subcortical nuclei in Parkinson’s disease, how this signature changes with effective therapies, and why personalized SCAN targeting may help refine non-invasive stimulation and circuit-guided interventions. The conversation explores implications for biomarkers, patient-specific targeting, and key unanswered questions that will shape the next generation of studies. Read the article.

Reviewing case reports and clinical series

Mon, 18 Apr 2022 00:00:00 EST

Dr. Daniel Di Luca discusses how to approach and review case reports and case series in movement disorders with Prof. Kailash Bhatia.

Revisiting the 2015 MDS clinical diagnostic criteria for Parkinson's disease

Mon, 02 Mar 2026 00:00:00 EST

Dr. Eduardo de Pablo-Fernández is joined by Dr. Susan Fox and Dr. Claudia Trenkwalder to discuss how to improve the current MDS clinical diagnostic criteria for Parkinson's disease. Read the article.

SCA3 & life in the countryside: Exploring the interplay between genetics and environment

Tue, 27 May 2025 00:00:00 EST

Dr. Sarah Camargos talks with Prof. Laura Bannach Jardim about how rural living might influence the age at onset of Machado-Joseph disease. Read the article.

Scar dancing syndrome

Sat, 09 Jan 2021 00:00:00 EST

Dr. Yiwen Wu discusses a newly-described peripherally-induced movement disorder (PIMD), and discusses with Dr. Schaefer the potential pathophysiologies of PIMDs. Read the article

Shame in Parkinson's disease: An unseen burden

Mon, 02 Feb 2026 00:00:00 EST

This episode explores shame as an often-overlooked but impactful non-motor symptom of Parkinson’s disease. Drawing on her team's recent research, Dr. Vanessa Fleury discusses the psychological and clinical determinants of shame, its strong link to quality of life, and why it deserves greater attention in routine care. The conversation highlights how recognizing and addressing shame may open new avenues for more holistic, patient-centered management. Read the article.

Skin tau as a biomarker of Huntington's disease

Fri, 06 Dec 2024 00:00:00 EST

Growing evidence suggests a contributory role of tau protein in the pathogenesis of Huntington's disease. In this episode, Dr. Eduardo de Pablo-Fernández discusses the potential role of skin tau quantification as a biomarker for Huntington's disease with Dr. Jaime Kulisevsky and Dr. Iñigo Ruiz-Barrio. The authors discuss the results of the recent study correlating skin tau quantification with clinical and radiological data, and the role of skin tau in defining HD subtypes. Read the article.

Sleep and Cognitive Decline | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

How can sleep predict cognitive decline in Parkinson's disease? Dr. Ron Postuma discusses his viewpoint and findings with Dr. Sarah Camargos at the MDS Congress.

Striatal Blood Brain Barrier Opening in Parkinson's Dementia

Tue, 20 Dec 2022 00:00:00 EST

Dr. Sara Schaefer discusses with Dr. Pineda-Pardo using focused ultrasound to temporarily open the striatal blood brain barrier in Parkinson's disease dementia patients, and the implications for the results of this safety and feasibility study including for future treatment options for these patients.
Journal CME is available until December 1, 2023 Read the article.

Surprise neuropathological findings in LRRK2 mutation carriers

Mon, 14 Jul 2025 00:00:00 EST

Mutations in LRRK2 are a common cause of familial and sporadic Parkinson’s. Though clinical features resemble typical PD, about half of cases lack Lewy pathology. Doctors Hiroaki Sekiya and Nanna Møller Jensen discuss their recent studies on the neuropathology of LRRK2-PD patients. They dive into their methods and how proximity ligation assays may compare to alpha-synuclein seeding assays in identification of alpha-synuclein oligomers. Together they explain their surprising results on how alpha-synuclein oligomers may be a key early feature in LRRK2-PD.
Read the first article.
Read the second article.

Swim for Parkinson: Swimming together to improve together

Mon, 18 Oct 2021 00:00:00 EST

The neurologists Dr. Francesca Morgante and Dr. Nicola Modugno and Cecilia Ferrari, a person with Parkinson's disease, share their experience swimming across the strait of Messina, highlighting the importance of physical activity in PD.

Targeting alpha synuclein in early Parkinson's disease. Clinical trials and future perspectives

Mon, 20 Mar 2023 00:00:00 EST

Two clinical trials with antibodies targeting alpha synuclein in early Parkinson's disease have been published in the New England Journal of Medicine. Anthony Lang and Gennaro Pagano, the first authors of the articles share the results and discuss the possible future perspectives with the MDS Podcast editor, Michele Matarazzo. Read the prasinezumab article. Read the cinpanemab article.

Task-specific brain oscillatory activity in laryngeal dystonia

Mon, 09 Oct 2023 00:00:00 EST

Laryngeal dystonia (LD) is a rare disorder affecting the vocal cords. Dr. Sarah Camargos sits down with Prof. Kristina Simonyan while she breaks down the methodology and findings of her comprehensive study investigating the temporal-spatial signature of LD. Read the article

Tau imaging for the study of corticobasal syndrome: The first steps of in vivo neuropathology

Mon, 13 Dec 2021 00:00:00 EST

Dr. Günter Hoglinger discusses the article he recently published in the Movement Disorders journal on tau imaging in a cohort of corticobasal syndrome patients, along with amyloid PET and CSF analysis to differentiate the neuropathological entity underlying the clinical manifestations. Read the article

tDCS for Tourette syndrome

Mon, 17 Mar 2025 00:00:00 EST

Dr. Sara Schaefer and Dr. Davide Martino discuss his recent paper exploring the use of transcranial direct current stimulation over the supplementary motor area for the suppression of tics in patients with Tourette Syndrome. Read the article.

The Basic Science Perspective on Future Therapeutic Targets | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

Basic science research for movement disorder therapies is booming. Prof. Tiago Outeiro asks Dr. Lorraine Kalia what therapeutic targets she thinks are stealing the stage at this year's MDS Congress.

The Basic Science Perspective on the Role of Alpha-Synuclein | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

The role of alpha-synuclein in various proteinopathies is still unknown. Prof. Poul Henning Jensen discusses this hot topic with Prof. Tiago Outeiro.

The cholinergic contribution to freezing of gait in Parkinson’s disease

Mon, 11 Aug 2025 00:00:00 EST

In this episode, host Dr. Michele Matarazzo interviews Dr. Nicolaas Bohnen about his team’s recent study using FEOBV PET to investigate cholinergic deficits in Parkinson’s disease patients with dopa-unresponsive freezing of gait (FOG). The results reveal a distinct pattern of cortical cholinergic denervation that may underlie this challenging and poorly treatable symptom. Dr. Bohnen discusses the implications for subtyping FOG, the role of cholinergic systems in higher-order motor control, and the potential for cholinergic-targeted therapies. Read the article.

The Ethics of Peer Review

Mon, 13 Jun 2022 00:00:00 EST

For this episode of our special series focused on the peer review process, Dr. Alana Kirby speaks with Prof. Claudia Trenkwalder about the ethics of peer review.

The evolution of tremor • 2024 MDS Congress

Mon, 07 Oct 2024 00:00:00 EST

Dr. Aasef Shaikh shares the exciting developments in the world of tremor and how he believes the use of technology will help answer some of the field’s big questions, including the personalization of treatment.

The Genetic Landscape of Complex Childhood-Onset Hyperkinetic Movement Disorders

Mon, 28 Nov 2022 00:00:00 EST

In this episode, Dr. Hugo Morales Briceño discusses the spectrum of phenotypes and genotypes of children with hyperkinetic movement disorders with Dr. Belén Pérez Dueñas and Prof. Manju Kurian. Read the article.

The impact of COVID-19 on scientific research activities

Fri, 06 Nov 2020 00:00:00 EST

In this interview, Prof. Brit Mollenhauer provides insight into how researchers have been coping with the COVID-19 pandemic. Read the article

The lasting impacts of scholarly debates - MDS 40th Anniversary

Mon, 01 Dec 2025 00:00:00 EST

To celebrate the 40th Anniversay of the MDS, Dr. Sara Schaefer sits down with two key leaders of the MDS European Regional Section, Prof. Marie Vidailhet and Prof. Alberto Albanese. Listen as they share their fond memories of scholarly debate, Congress experiences, and hopes for the future.

The longest prospective study of pallidal DBS for isolated dystonia

Mon, 04 Aug 2025 00:00:00 EST

Dr. Mitra Afshari interviews Drs. Patricia Krause and Andrea Kühn on the results of a 10-year prospective follow-up study of a multicenter trial of GPI-DBS in isolated generalized and segmental dystonia. Together they discuss motor, non-motor, and safety outcomes, as well as the strong and stable long-term improvements in dystonia from pallidal DBS. Further, they provide their expert insights on the common themes with respect to treatment failure and the critical need for a personalized approach.
Journal CME is available until June 19, 2026
Read the article.

The Mediterranean diet in Parkinson's disease

Mon, 11 Feb 2019 00:00:00 EST

Dr. Nikolaos Scarmeas discusses with Dr. Michele Matarazzo the results of his article about the impact of the Mediterranean diet on the risk of Parkinson’s disease, published in the January 2019 issue of the Movement Disorders journal. Read the article

The most impactful paper related to movement disorders therapy in the 20th century

Mon, 18 Oct 2021 00:00:00 EST

Dr. Sara Schaefer speaks with Dr. Stanley Fahn about the origins of levodopa therapy for Parkinson's disease in the 1960s, how that generated an explosion of interest and research in dopamine's role in movement disorders and beyond, and how it all led to the dawning of the movement disorders field, journal, society, and community that we are all part of today. Read the article

The Role of Levodopa Challenge in Predicting the Outcome of STN DBS

Mon, 25 Sep 2023 00:00:00 EST

Dr. Eduardo Fernandez interviews Professor Günther Deuschl and Dr. Robin Wolke on their recent MDCP article on the challenges levodopa poses when predicting the outcome of subthalamic deep brain stimulation. Read the article

The role of young members in the peer review process

Mon, 30 May 2022 00:00:00 EST

For this episode of the special series focused on peer reviews, Dr. Daniel Di Luca speaks with Prof. Marcelo Merello about the role of young members and trainees in the peer review process.

The treatment of upper limb tremor with botulinum toxin: An individualized approach

Fri, 01 Nov 2019 00:00:00 EST

Dr. Sara Schaefer discusses with Dr. Jordan Kamel the role of botulinum toxin in the treatment of refractory upper limb tremor, and his center's tailored approach to provide relief for these patients. Read the article

The wisdom of our mentors: clinical pearls in movement disorders

Mon, 25 Mar 2024 00:00:00 EST

In this episode, Dr. Hugo Morales interviews Dr. Bas Bloem and Dr. Victor Fung, co-authors of "The Wisdom of Our Mentors: Clinical Pearls in Movement Disorders," who share clinical pearls and discuss how mentors' and mentees' interactions are at the center of mentorship in movement disorders and the MDS. Read the article

Tic disorders and Tourette syndrome | Congress 2019

Wed, 06 Nov 2019 00:00:00 EST

As part of the MDS Congress 2019 Special Issue, Dr. Michele Matarazzo interviews Dr. Christos Ganos about the newly created MDS Tic Disorders and Tourette Syndrome Study Group, and the main news breakthroughs in the field, that have been discussed during the MDS Congress.

TikTok tics

Sun, 01 Aug 2021 00:00:00 EST

Dr. Sara Schaefer speaks with Dr. Caroline Olvera about trending videos of tics and other neurological syndromes on social media. Read the article

Transcutaneous spinal cord stimulation for essential tremor

Mon, 11 Nov 2024 00:00:00 EST

Dr. Anna Latorre is interviewed by Dr. Sara Schaefer about her study exploring the role of transcutaneous spinal cord simulation for suppression of postural tremor in essential tremor, including the potential pathophysiological mechanisms and implications for therapeutic use.
Journal CME is available until October 21, 2025 Read the article.

Tremor | Congress 2019

Wed, 06 Nov 2019 00:00:00 EST

As part of the MDS Congress 2019 Special Issue, Dr. Michele Matarazzo interviews Dr. Rodger Elble about recent advances in tremor classification, diagnosis and treatment approaches, and about the future plans of the MDS Tremor study group to overcome current challenges for clinicians and researchers.

Tremor Series: How do we shake? The pathophysiology of tremor

Mon, 18 Nov 2024 00:00:00 EST

Dr. Rick Helmich tells us about the role of functional MRI in understanding the circuits of tremor. The conversation starts with a description of his most famous theory on the pathophysiology of Parkinsonism tremor ('dimmer-switch' hypothesis) and moves towards other forms of tremors, such as dystonic, Holmes and essential and even physiological tremor.

Tremor Series: So common, so difficult: The phenomenology of tremor

Mon, 02 Dec 2024 00:00:00 EST

In this episode Dr. Alfonso Fasano interviews Dr. Petra Schwingenschuh on her approach to tremor in the clinic. She further explains the importance of a good history taking, how to clinically assess tremor of different body parts, and how to diagnose functional tremor.

Tremor Series: The novel pharmacological and surgical treatments for tremor

Mon, 06 Jan 2025 00:00:00 EST

In this episode Dr. Ludy Shih briefly describes the current approach to tremor, including pharmacological treatments, botulinum toxin injections and deep brain stimulation. She further dives into the exciting new developments of the past few years and new drugs coming down the pipeline.

Tremor Series: What’s essential tremor?

Mon, 16 Dec 2024 00:00:00 EST

In this episode, the two souls at the center of the new tremor classification join the MDS Podcast to discuss what essential tremor is. Listen as Prof. Kailash Bhatia and Prof. Günther Deuschl walk you through their clinical methods and future outlook on essential tremor. Do they agree? Disagree?

Tremor Series: What's in store? The future of tremor research

Mon, 20 Jan 2025 00:00:00 EST

In this episode, Dr. Aasef Shaikh and Dr. Ming-Kai Pan give us a virtual guided tour of their labs, particularly discussing what they are presently working on. They further elaborate on how these studies can inform our understanding of tremor physiology and where they believe the field should be heading in order to finally understand tremor origin.

Tremor Series: Why tremor?

Mon, 04 Nov 2024 00:00:00 EST

In the introductory episode for the Tremor Special Series, Dr. Elan Louis tells us about the epidemiology of tremor as well as patients' and health care providers' awareness (or lack thereof). He guides us through his journey from when his mentor suggested that he'd look into familial essential tremor to the most important discoveries of the last two decades. Finally he gives us a glimpse of what's about to come and why tremor matters.

Understanding corticobasal syndrome: Clinical and neuroimaging characteristics to unlock the underlying pathology

Mon, 10 Jun 2024 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Jacy Parmera about her recently published article on the clinical and neuroimaging characteristics of patients with corticobasal syndrome, with a focus on the potential correlation with the underlying neuropathological causes. Read the article »

Unmet needs of women with Parkinson's disease: Gaps and controversies

Mon, 23 May 2022 00:00:00 EST

Dr. Sarah Lidstone interviews Dr. Indu Subramanian about her recent paper, "Unmet needs of women with Parkinson's disease: Gaps and Controversies," in Movement Disorders. Read the article.

Unravelling the progression of tremor in Parkinson's disease

Mon, 18 Dec 2023 00:00:00 EST

Dr. Pasquini discusses the findings of his collaborative study that has helped to understand the progression of rest postural and kinetic tremor in Parkinson's disease. Read the article

Update from the Synuclein Meeting 2022

Mon, 20 Jun 2022 00:00:00 EST

In this episode we interviewed Prof. Veerle Baekelandt from KU Leuven, Belgium, who was the main organizer of the Synuclein Meeting 2022. We discussed the major highlights of the meeting, what to expect in the coming years, and what are the major questions still to be addressed.

Updates in Gene Therapy | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

What gene therapies are the most promising the field of movement disorders? Dr. Sarah Camargos met with Prof. Deniz Kirk at the 2023 MDS Congress to get his perspective on how the field of gene therapy has evolved over the years and where it has yet to go.

Updates in MDS Education | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

Dr. Sara Schaefer sits down with Prof. Carolyn Sue and Dr. Shilpa Chitnis to discuss the newest offerings in MDS Education; the MDS Career Development and LEAP Programs.

Updates in PSP and Atypical PD • 2024 MDS Congress

Mon, 07 Oct 2024 00:00:00 EST

Dr. Günter Höglinger discusses new genetic findings and other exciting research surrounding PSP and other atypical parkinsonisms.

Updates in tauopathies • 2025 MDS Congress

Mon, 20 Oct 2025 00:00:00 EST

Dr. Yaroslau Compta discusses how the view of co-pathologies has changed the view of many disorders, including tauopathies. He dives into the current state of clinical trials for PSP and what those results may mean for the future of biomarkers.

Updates in Tremor Treatments | Congress 2023

Mon, 18 Sep 2023 00:00:00 EST

What new research is coming that may change the way clinicians treat tremor? Dr. Tiago Mestre shares his perspective on tremor treatment research with Dr. Hugo Morales.

Updates of Functional Movement Disorders | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

The lines between functional and organic are blurring, as a promising opportunity to develop outcome measurements arises. Dr. Alberto Espay discusses with Dr. Sara Schaefer these and other advancements in functional movement disorders.

Updates on Dystonia | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

Promising results on potential treatments, biomarkers, genetic predictors and more in dystonia were presented at the MDS Congress. Dr. Florence Chang highlights the key takeaways with Dr. Hugo Morales.

Updates on Multiple System Atrophy Research | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

New updates to MSA criteria and clinical evaluation tools will have a critical impact on MSA care and research. Dr. Maria Teresa Pellecchia discusses with Dr. Eduardo de Pablo-Fernández the next major areas of focus, and the progression of a variety of clinical trials.

Using alcohol as a tool to unravel laryngeal dystonia: The Vodka Trial

Mon, 10 Nov 2025 00:00:00 EST

In this episode, Dr. Divyani Garg converses with Prof. Kristina Simonyan on applying the standard alcohol challenge test, in combination with targeted genetic analysis in the GABAergic synapse pathways, in persons with laryngeal dystonia. Together they explore alcohol’s role in laryngeal dystonia, the genetic signatures that may predict responsiveness, and what this could mean for the future of treatment of laryngeal dystonia specifically, but also dystonia in general. Read the article.

Using EEG to Identify Parkinson's Subtypes

Mon, 04 Dec 2023 00:00:00 EST

Dr. Sara Schaefer discusses with Prof. Marc Vérin and Prof. Mahmoud Hassan their recent paper in Movement Disorders Journal on the use of Resting-State High-Density EEG to neurophysiologically stratify Parkinson's patients into subtypes in an effort to predict cognitive and motor progression, properly evaluate for invasive therapies, and inform future clinical research. Read the article

Value of invivosynuclein deposits in Parkinson's disease - Asystematic review and metaanalysis

Wed, 14 Oct 2020 00:00:00 EST

Dr. Michele Matarazzo interviews Dr. Kazuto Tsukita, the first author of the article awarded as "2020 Review Article from Movement Disorders" on the advances of in-vivo alpha-synuclein detection as a biomarker for Parkinson. Read the article

Variability of movement disorders: The influence of sensation

Mon, 18 Oct 2021 00:00:00 EST

Dr. Michele Matarazzo speaks with Prof. Maja Kojović about the paper awarded as 2021 best review article from the Movement Disorders journal, highlighting the impact on several factors on the variability of movement disorders. Read the article

Vibrotactile foot stimulation for freezing of gait

Mon, 03 Feb 2025 00:00:00 EST

Dr. Chan joins the podcast to discuss the results of their pilot study with Dr. Eduardo De Pablo-Fernández. The study uses a foot vibrotactile stimulation as an external cue for the treatment of freezing of gait in Parkinson's disease. Together they discuss how vibrotactile devices can be implemented in clinical practice. Read the article.

Video-based machine learning for tic detection

Mon, 27 Jan 2025 00:00:00 EST

In this episode, Prof. Alexander Münchau talks about how machine learning video-based assessments can be leveraged to quantify tics in Tourette syndrome and how this technology has the potential to assist clinicians in tic detection. Read the article.

Walking through the falls: understanding gait with wearable sensors in Parkinson's disease

Mon, 27 Mar 2023 00:00:00 EST

In this paper, Dr. Vrustangkumar Shah and colleagues evaluated gait in patients with Parkinson's disease in the lab and in real life, with and without levodopa through wearable sensors. Some measures are able to discriminate fallers from non-fallers in PD. Read the article.

Waveform-based analysis of head tremor using a marker-less tracking algorithm with 2D-video

Mon, 15 Dec 2025 00:00:00 EST

Differentiating a dystonic head tremor from a head tremor in essential tremor can sometimes be diagnostically challenging. In this episode, Dr. Mitra Afshari interviews Dr. Jung Hwan Shin and Prof. Beomseok Jeon on their investigation into the rhythmicity and sinusoidality of head tremors in cervical dystonia versus essential tremor using simple 2D video recordings. We’ll hear about how their findings fit their original hypotheses and potential future work that the group has been brainstorming. Journal CME is available until November 26, 2026
Read the article.

What are journal editors looking for in a good review?

Mon, 04 Apr 2022 00:00:00 EST

This is the third episode of the special series focused on the peer review process. In this episode, Dr. Alana Kirby speaks with Dr. Jon Stoessl about what journal editors are looking for in a good review. He provides practical tips for writing an effective peer review.

What can the locus coeruleus tell us about cognition in Lewy body disorders?

Mon, 28 Apr 2025 00:00:00 EST

Dr. Michele Matarazzo interviews Prof. Irena Rektorová about her recent study on early changes in the locus coeruleus in mild cognitive impairment with Lewy bodies. Using neuromelanin-sensitive MRI, the study reveals selective vulnerability of the caudal locus coeruleus and its association with specific cognitive and other nonmotor features. The conversation explores the implications for early diagnosis, the “body-first” hypothesis, and the potential role of NM-MRI as a biomarker. Read the article.

What is it? Exercise-induced episodic gait disorder in a young boy

Mon, 16 Feb 2026 00:00:00 EST

A young boy presents with exercise-induced episodic gait disturbance. Dr. Shekeeb Mohammad analyses the clinical phenomenology alongside laboratory and neuroimaging findings, systematically exploring the differential diagnosis before arriving at the final diagnosis.

What you missed: MDS Congress Day 1

Sat, 28 Sep 2024 00:00:00 EST

The first day of the #mdscongress has come to a close. Listen as Dr. Davide Martino recalls the exciting topics discussed in the plenaries; including treatment for early PD, device aided therapies, dystonia and tremor.

What you missed: MDS Congress Day 1

Mon, 06 Oct 2025 00:05:00 EST

An eventful first day of the 2025 #mdscongress has come to a close. Listen here as Dr. Davide Martino reviews the events and interesting scientific sessions for those near and far. Don’t miss out!

What you missed: MDS Congress Day 2

Sun, 29 Sep 2024 00:00:00 EST

The second day of #mdscongress was filled with various sessions and activities, including the presidential lectures & networking events. Dr. Michiko Bruno shares her appreciation for MDS camaraderie, and which sessions caught her eye.

What you missed: MDS Congress Day 2

Tue, 07 Oct 2025 00:00:00 EST

Prof. Francesca Morgante breaks down the second day of the #mdscongress which included the presidential lectures, junior awardees, and several enlightening teaching sessions.

What you missed: MDS Congress Day 3

Mon, 30 Sep 2024 00:00:00 EST

Informative plenaries, exciting grand rounds and a historical faculty dinner filled the third day of the #mdscongress. Prof. Irena Rektorova shares her favorite moments and key takeaways.

What you missed: MDS Congress Day 3

Wed, 08 Oct 2025 00:00:00 EST

Dr. Huw Morris discusses the session highlights from #mdscongress day three, which included a plenary session on protein aggregation clearance, movement disorder grand rounds, and several exciting oral platforms.

What you missed: MDS Congress Day 4

Tue, 01 Oct 2024 00:00:00 EST

The last full day of #mdscongress 2024 was packed full of sessions and other activities. Prof. Huw Morris dives into the learnings from the day and recollects the excitement surrounding the much-loved Video Challenge.

What you missed: MDS Congress Day 4

Thu, 09 Oct 2025 12:00:00 EST

The last full day of the #mdscongress was full of exciting sessions and events. Dr. Laura Silveira-Moriyama shares her excitement about the keynote speaker, updates on disease modifying clinical trials, and of course, the crowd pleasing MDS Video Challenge.

What’s new for MSA? • 2025 MDS Congress

Mon, 27 Oct 2025 00:00:00 EST

Prof. Alessandra Fanciulli discusses how the MDS criteria for the diagnosis of MSA has made an impact on the field, the status of biomarker research, and optimal targets for disease-modifying trials for MSA.

What's new in the pathophysiology of Parkinson's disease? • 2024 MDS Congress

Mon, 07 Oct 2024 00:00:00 EST

Alpha-synuclein based biomarkers have dominated the Parksinon's disease field over the past few years. Dr. Andrew Siderowf shares his views on the future of these biomarkers and what else the field may have in store.

What's next? Updates in functional neuroimaging • 2025 MDS Congress

Mon, 27 Oct 2025 00:00:00 EST

Developments in neuroimaging have grown a lot over the years. Dr. Thilo van Eimeren discusses biomarker development, both in tau and alpha synuclein, current research, and his hope for future successes.

When should dopaminergic treatment be initiated in Parkinson's disease?

Tue, 30 Apr 2019 00:00:00 EST

Dr. Ruth Schneider discusses with Dr. Sara Schaefer about the article she recently published in the Movement Disorders Clinical Practice that investigates the outcomes of early vs delayed start of dopaminergic medication in Parkinson's disease. Read the article

When to accept or decline an invitation to review

Mon, 21 Mar 2022 00:00:00 EST

For the second episode of the special series focused on the peer review process, Dr. Shweta Prasad speaks with Prof. Günther Deuschl about the crucial first part of the peer review process - identifying reviewers, and understanding when a reviewer should accept or decline an invitation to review.

Which protein is it? Copathologies • 2024 MDS Congress

Mon, 07 Oct 2024 00:00:00 EST

Prof. Jeffrey Kordower shares the data in support of #PD being a copathology disease and what strategies may be in the future for protein aggregate clearance in age-related neurodegenerative diseases.

White matter changes in Huntington's disease

Mon, 20 Jan 2020 00:00:00 EST

Dr. Sara Schaefer discusses with Dr. Sarah Gregory her recent study on neuroimaging changes and fluid biomarkers in Huntington's disease, and how those may be used to better characterize the biological basis for neurodegeneration in this disease Read the article

World Movement Disorders Day: How to fight stigma in Parkinson's disease

Tue, 26 Nov 2024 00:00:00 EST

Dr. Indu Subramanian shares her view on stigma affecting people with Parkinson's disease, along with some practical tips on how to fight it as doctors and as a society.

World Movement Disorders Day: Stigma in movement disorders

Mon, 25 Nov 2024 00:00:00 EST

Dr. Natasha Fothergill-Misbah discusses stigma in movement disorders with Dr. Sara Schaefer, including the origins, types, and consequences of stigma, and how stigma may be perpetuated and combatted around the world.

World Movement Disorders Day: Stigma in pediatric movement disorders

Wed, 27 Nov 2024 00:00:00 EST

Dr. Sara Schaefer interviews Dr. Jaclyn Martindale on stigma in the experiences of individuals with pediatric movement disorders and tic disorders. They discuss the reasons behind stigma, types of stigma, and ways that stigma is perpetuated and mitigated in this special episode for World Movement Disorders Day 2024.

New Technology in Movement Disorders | Congress 2022

Sat, 01 Oct 2022 00:00:00 EST

Wearable sensors, electronic rating scales, eDiaries — Dr. Álvaro Sánchez-Ferro discusses with Dr. Michele Matarazzo how these and a broad range of other emerging digital technologies can help take movement disorder evaluation outside the clinic and into patients' everyday environment.