Non-Motor Symptoms Questionnaire (NMSQ)
Acronym: NMSQ, NMSQuest
Authors: Kallol Ray Chaudhuri, Pablo Martinez-Martin, Anthony H.V. Schapira, Fabrizio Stocchi, Kapil Sethi, Per Odin, Richard G. Brown, William Koller, Paolo Barone, Graeme MacPhee, Linda Kelly, Martin Rabey, Doug MacMahon, Sue Thomas, William Ondo, David Rye, Alison Forbes, Susanne Tluk, Vandana Dhawan, Annette Bowron, Adrian J. Williams, and Charles W. Olanow: Members of the International PD Non-Motor Group.
The Non-Motor Symptoms Questionnaire (NMSQ) enables clinicians to complete a comprehensive assessment of a diverse range of non-motor symptoms which can occur in all stages of Parkinson’s disease. It is a patient-based screening tool designed to draw attention to the presence of non-motor symptoms in patients for further investigation or treatment. It is not designed to assess the severity of symptoms or measure the effect of treatment.
Original Publication │View the Scale (PDF)
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Year Published: 2006
Scale Last Updated: Unchanged since publication
Assessment Type: PRO
Estimated Time to Complete: 5-7 minutes
Additional Scale Publications:
Chaudhuri KR, Schapira AHV, Martinez-Martin P, et al. Can We Improve the Holistic Assessment of Parkinson’s Disease? The development of a non-motor symptom questionnaire and scale for Parkinson’s disease. ACNR 2004;4(4):20-5.
Chaudhuri KR, Yates L, Martinez-Martin P. The non-motor symptom complex of Parkinson's disease: A comprehensive assessment is essential. Curr Neurol Neurosci Rep. 2005 Jul;5(4):275-83.
Martinez-Martin P, Schapira AH, Stocchi F, Sethi K, Odin P, Macphee G, Brown RG, Naidu Y, Clayton L, Abe K, Tsuboi Y, Macmahon D, Barone P, Rabey M, Bonuccelli U, Forbes A, Breen K, Tluk S, Olanow CW, Thomas S, Rye D, Hand A,Williams AJ, Ondo W, Chaudhuri KR. Prevalence of nonmotor symptoms in Parkinson's disease in an international setting: Study using nonmotor symptoms questionnaire in 545 patients. Movement Disorders 2007 Aug 15;22(11):1623-9.
Chaudhuri KR, Martinez‐Martin P. Quantitation of non‐motor symptoms in Parkinson’s disease. European Journal of Neurology. 2008 Sep;15:2-8.
Lloret SP, Rossi M, Cardinali DP, Merello M. Validation of the sleep related items of the Non-motor Symptoms Questionnaire for Parkinson's disease (NMSQuest). Parkinsonism & related disorders. 2008 Dec 1;14(8):641-5.
Romenets SR, Wolfson C, Galatas C, Pelletier A, Altman R, Wadup L, Postuma RB. Validation of the Non-Motor Symptoms Questionnaire (NMS-Quest). Parkinsonism & Related Disorders. 2012 Jan 1;18(1):54-8.
Crosiers D, Pickut B, Theuns J, Deyn PP, Van Broeckhoven C, Martinez-Martin P, Chaudhuri KR, Cras P. Non-motor symptoms in a Flanders-Belgian population of 215 Parkinson's disease patients as assessed by the Non-Motor Symptoms Questionnaire. Am J Neurodegener Dis. 2012;1(2):160-7.
Chaudhuri KR, Sauerbier A, Rojo JM, Sethi K, Schapira AH, Brown RG, Antonini A, Stocchi F, Odin P, Bhattacharya K, Tsuboi Y. The burden of non-motor symptoms in Parkinson's disease using a self-completed non-motor questionnaire: a simple grading system. Parkinsonism & related disorders. 2015 Mar 1;21(3):287-91.
Li HJ, Zhang MF, Chen MX, Hu AL, Li JB, Zhang B, Liu W. Validation of the nonmotor symptoms questionnaire for Parkinson's disease: results from a Chinese pilot study. Int J Neurosci. 2015;125(12):929-35.
Cova I, Di Battista ME, Vanacore N, Papi CP, Alampi G, Rubino A, Valente M, Meco G, Contri P, Di Pucchio A, Lacorte E, Priori A, Mariani C, Pomati S. Adaptation and psychometric properties of the Italian version of the Non-Motor Symptoms Questionnaire for Parkinson's disease. Neurol Sci. 2017 Apr;38(4):673-678.