The Movement Disorder Society Genetic mutation database (MDSGene) aims to provide a comprehensive, systematic overview of published data on movement disorder patients reported to carry causative gene mutations. MDSGene currently contains data on over 1000 different mutations in over 6000 movement disorder patients extracted from over 1000 publications. For more information, visit the MDSGene website.
Disease categories of interest with available genetic and clinical data include:
- Chorea (Benign hereditary chorea) (CHOR)
- Dystonia (DYT)
- Dystonia/parkinsonism (DYT/PARK)
- Hereditary spastic paraplegia (HSP)
- Parkinsonism (PARK)
- Paroxysmal movement disorders (PxMD)
- Primary familial brain calcification (PFBC) – associated movement disorder
Data continues to be added to MDSGene.
The development and curation of MDSGene was supported by the International Parkinson and Movement Disorder Society (MDS). Note that neither the MDS nor the scientists in charge of content curation assume any liability for the relevance, accuracy, completeness or quality of the information provided on this database. See legal disclaimer for further information.
MDSGene may be used for individual, personal, educational, research, and nonpecuniary purposes only and is free for MDS members for non-commercial purposes. MDSGene may not be used in whole or in part for commercial purposes without the expressed, written permission in advance from MDSGene. Licensing requests should be sent by way of the Contact Us form.