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Journal CME 41.08: Distinct brain drivers and shared cerebello-cortical input in ADCY5 and SGCE hyperkinetic movements
On Demand
Journal CME
60 Minutes
Experienced / Intermediate
CME Credits:1.001158 <p>The Journal CME 41.08 article aims to determine how basal ganglia and cerebellar dysfunction drives cortical dysregulation in hyperkinetic movement disorders.</p> Basal Ganglia, Basic/Translational Neuroscience, Chorea/Huntingtons Disease (HD), Dystonia, Etiology & Pathophysiology, Genetics, Hyperkinetic Movement Disorders, Myoclonus, Neuropsychiatric symptoms, Non-motor Symptoms/Disorders, Tics/Tourettes syndrome (TS), Tremor/Essential Tremor (ET) Clément Tarrano, MD, PhD, 60 1.00 https://education.movementdisorders.org/Detail/1158/Journal-CME-41-08:-Distinct-brain-drivers-and-shared-cerebello-cortical-input-in-ADCY5-and-SGCE-hyperkinetic-movements https://education.movementdisorders.org/Upload/ActivityImages/Journal-CME562837664663.jpg 2026-10-14T00:00:00 2027-10-14T00:00:00 <p><strong>ACCREDITATION STATEMENT</strong></p><p>This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME). The International Parkinson and Movement Disorder Society is accredited by the ACCME to provide continuing medical education for physicians.</p><p><br></p><p><strong>CREDIT DESIGNATION STATEMENT</strong></p><p>The International Parkinson and Movement Disorder Society designates this activity for a maximum of 1 <em>AMA PRA Category 1 Credits™</em>. Physicians should only claim credit commensurate with the extent of their participation.</p><p><br></p><p><strong>FACULTY DISCLOSURE</strong></p><p>All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available <a href="https://d1t84l7yt030ad.cloudfront.net/FroalaFiles/Journal%20CME%2041.08-002%20-%20Disclosures_29092026024901.pdf" rel="noopener noreferrer" target="_blank"><u>HERE</u></a>. All relevant financial relationships have been mitigated in advance of this program.</p><p><br></p><p><strong>METHOD OF PARTICIPATION</strong></p><p>Each module will take approximately one (1) hour to complete. Upon reading the article, participants will take a post-test and must receive a grade of 75% or higher to pass. Participants are allowed multiple attempts to complete the post-test. Once the post-test is passed, participants are required to complete the module evaluation.</p><p><br></p><p><strong>SATISFACTORY COMPLETION</strong></p><p>Participants must complete an evaluation for each session they attend to receive continuing medical education credit. Your chosen session(s) must be attended in their entirety. Partial credit for individual sessions is not available.</p><p><br></p><p><strong>CONTENT VALIDITY STATEMENT</strong></p><p>All recommendations involving clinical medicine in MDS activities are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the case of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendations conforms to the generally accepted standards of experimental design, data collection and analysis. Activities that promote recommendations, treatment or manners of practicing medicine not within the definition of CME or are knowing to have risks or dangers that outweigh the benefits or are knowing to be ineffective in the treatment of patients do not constitute valid CME.</p> MDS Education <p><strong>COURSE PURPOSE</strong></p><p>Journal CME highlights various articles covering relevant issues, developments and research topics in the area of movement disorders. Articles are selected from Movement Disorders, the official Journal of the International Parkinson and Movement Disorder Society.</p><p><br></p><p><strong>LEARNING OBJECTIVES</strong></p><p>Upon completion of this activity, learners will be able to:</p><p>1. Understand the psychiatric manifestations and brain regions involved in ADCY5- and SGCE-related hyperkinetic movement disorders</p><p>2. Assess the cortical and subcortical nodes involved in motor and non-motor networks in these disorders</p><p>3. Evaluate the role of the cerebellum in the pathophysiology of SGCE-related hyperkinetic movements</p><p><br></p><p><strong>INTENDED AUDIENCE</strong></p><p>This activity is intended for clinicians, other health professionals, researchers, policy makers from throughout the world, both MDS members and non-members, who interact with patients living with Movement Disorders.</p><p><br></p><p><strong>HARDWARE AND SOFTWARE REQUIREMENTS</strong></p><p>1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.</p><p>2. Compatible with Windows PC and MAC (256 MB of RAM or higher).</p><p>3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher.</p><p>4. Adobe Flash Player 12.0 (or higher).</p><p>5. Adobe Reader to print certificate.</p> 0 /Courses/Journal-CME-41.08-Distinct-brain-drivers-and-shared-cerebello-cortical-input-in-ADCY5-and-SGCE-hyperkinetic-movements.htm Journal CME 41.08: Distinct brain drivers and shared cerebello-cortical input in ADCY5 and SGCE hyperkinetic movements Journal CME 41.08 2026-10-14T18:00:59.510 0 0 Experienced / Intermediate Journal CME CME English On-Demand Clinician Fellow Industry Researcher Resident USA
Journal CME 41.09: Transcranial Stimulation enhances dexterity in Parkinson's disease: A randomized sham-controlled trial
On Demand
Journal CME
60 Minutes
Experienced / Intermediate
CME Credits:1.001157 <p>The Journal CME 41.09 article aims to evaluate the effects of repeated transcranial pulse stimulation (TPS) applications on motor symptoms, brain structure, and functional activation in PD.</p> Biomarkers & Diagnostic Tools, Neuroimaging, Non-invasive stimulation, Parkinson Disease/Hypokinetic Movement Disorders, Parkinson's Disease (PD), Rating Scales, Therapies-Other Eva Matt, PhD 60 1.00 https://education.movementdisorders.org/Detail/1157/Journal-CME-41-09:-Transcranial-Stimulation-enhances-dexterity-in-Parkinson's-disease:-A-randomized-sham-controlled-trial https://education.movementdisorders.org/Upload/ActivityImages/Journal-CME562837664663.jpg 2026-10-14T00:00:00 2027-10-14T00:00:00 <p><strong>ACCREDITATION STATEMENT</strong></p><p>This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME). The International Parkinson and Movement Disorder Society is accredited by the ACCME to provide continuing medical education for physicians.</p><p><br></p><p><strong>CREDIT DESIGNATION STATEMENT</strong></p><p>The International Parkinson and Movement Disorder Society designates this activity for a maximum of 1 <em>AMA PRA Category 1 Credits™</em>. Physicians should only claim credit commensurate with the extent of their participation.</p><p><br></p><p><strong>FACULTY DISCLOSURE</strong></p><p>All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available <a href="https://d1t84l7yt030ad.cloudfront.net/FroalaFiles/Journal%20CME%2041.09%20-%20Disclosures_14102026031626.pdf" rel="noopener noreferrer" target="_blank"><u>HERE</u></a>. All relevant financial relationships have been mitigated in advance of this program.</p><p><br></p><p><strong>METHOD OF PARTICIPATION</strong></p><p>Each module will take approximately one (1) hour to complete. Upon reading the article, participants will take a post-test and must receive a grade of 75% or higher to pass. Participants are allowed multiple attempts to complete the post-test. Once the post-test is passed, participants are required to complete the module evaluation.</p><p><br></p><p><strong>SATISFACTORY COMPLETION</strong></p><p>Participants must complete an evaluation for each session they attend to receive continuing medical education credit. Your chosen session(s) must be attended in their entirety. Partial credit for individual sessions is not available.</p><p><br></p><p><strong>CONTENT VALIDITY STATEMENT</strong></p><p>All recommendations involving clinical medicine in MDS activities are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the case of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendations conforms to the generally accepted standards of experimental design, data collection and analysis. Activities that promote recommendations, treatment or manners of practicing medicine not within the definition of CME or are knowing to have risks or dangers that outweigh the benefits or are knowing to be ineffective in the treatment of patients do not constitute valid CME.</p> MDS Education <p><strong>COURSE PURPOSE</strong></p><p>Journal CME highlights various articles covering relevant issues, developments and research topics in the area of movement disorders. Articles are selected from Movement Disorders, the official Journal of the International Parkinson and Movement Disorder Society.</p><p><br></p><p><strong>LEARNING OBJECTIVES</strong></p><p>Upon completion of this activity, learners will be able to:</p><p>1. Understand the advantages and potential applications of TPS compared with other noninvasive brain stimulation approaches</p><p>2. Assess the study design, eligibility criteria, and imaging methods used to evaluate TPS in Parkinson’s disease</p><p>3. Evaluate changes in motor activation and white matter integrity following TPS, including findings from fMRI and DTI</p><p><br></p><p><strong>INTENDED AUDIENCE</strong></p><p>This activity is intended for clinicians, other health professionals, researchers, policy makers from throughout the world, both MDS members and non-members, who interact with patients living with Movement Disorders.</p><p><br></p><p><strong>HARDWARE AND SOFTWARE REQUIREMENTS</strong></p><p>1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.</p><p>2. Compatible with Windows PC and MAC (256 MB of RAM or higher).</p><p>3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher.</p><p>4. Adobe Flash Player 12.0 (or higher).</p><p>5. Adobe Reader to print certificate.</p> 0 /Courses/Journal-CME-41.09-Transcranial-Stimulation-enhances-dexterity-in-Parkinsons-disease-A-randomized-sham-controlled-trial.htm Journal CME 41.09: Transcranial Stimulation enhances dexterity in Parkinson's disease: A randomized sham-controlled trial Journal CME 41.09 2026-10-14T18:00:57.963 0 0 Experienced / Intermediate Journal CME CME English On-Demand Clinician Fellow Industry Researcher Resident USA
Approach and Management of Restless Legs Syndrome
On Demand
Interactive
60 Minutes
Foundational / Beginner
CME Credits:1.001133 <p>This course offers an in-depth exploration of Restless Legs Syndrome (RLS), covering the pathophysiology of RLS, latest diagnostic criteria, key differential diagnoses, and evidence-based treatment approaches, including pharmacological and non-pharmacological options.<br /></p> Other Movement Disorders, Restless Legs Syndrome (RLS)/Periodic Limb Movement Disorder (PLMD) Luigi Ferini-Strambi, MD, Maria Paola Mogavero, MD, PhD 60 1.00 https://education.movementdisorders.org/Detail/1133/Approach-and-Management-of-Restless-Legs-Syndrome https://education.movementdisorders.org/Upload/ActivityImages/05INTERACT-51-001-rls-202x1087655.jpg 2026-09-18T00:00:00 2029-09-18T00:00:00 <p><strong>CREDIT DESIGNATION STATEMENT</strong></p><p>The International Parkinson and Movement Disorder Society designates this activity for a maximum of 1 <em>AMA PRA Category 1 Credits™</em>. Physicians should only claim credit commensurate with the extent of their participation.</p><p><br></p><p><strong>FACULTY DISCLOSURE</strong></p><p>All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available <a href="https://d1t84l7yt030ad.cloudfront.net/FroalaFiles/Final Disclosure Block_Approach and Management of Restless Legs Syndrome_16092026115929.pdf" rel="noopener noreferrer" target="_blank">HERE</a>. All relevant financial relationships have been mitigated in advance of this program.</p><p><br></p><p><strong>SATISFACTORY COMPLETION</strong></p><p>Participants must complete an evaluation for each session they attend to receive continuing medical education credit. Your chosen session(s) must be attended in their entirety. Partial credit for individual sessions is not available.</p><p><br></p><p><strong>METHOD OF PARTICIPATION </strong></p><p>Your chosen sessions must be attended in their entirety. Partial credit of individual sessions is not available. If you are seeking continuing education credit for a specialty not listed in the Accreditation Statement, it is your responsibility to contact your licensing/certification board to determine course eligibility for your board requirement.</p><p><br></p><p><strong>CONTENT VALIDITY STATEMENT</strong></p><p>All recommendations involving clinical medicine in MDS activities are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the case of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendations conforms to the generally accepted standards of experimental design, data collection and analysis. Activities that promote recommendations, treatment or manners of practicing medicine not within the definition of CME or are knowing to have risks or dangers that outweigh the benefits or are knowing to be ineffective in the treatment of patients do not constitute valid CME.</p> MDS Education <p><span style="background-color: null;"><strong>FACULTY</strong></span></p><p><span style="background-color: null;">Luigi Ferini-Strambi, MD - Vita Salute Raffaele Turro - Milan, Italy</span></p><p>Maria Paola Mogavero, MD, PhD - Oasi Research Institute IRCCS, Troina, Italy, Adjunct Professor of Neurology, University of Milan, Italy</p><p><br></p><p><strong>LEARNING OBJECTIVES</strong></p><p>Upon the completion of this activity, learners will be able to:</p><p>1. Explain the epidemiology, causes, and pathophysiology of RLS.</p><p>2. Apply disgnostic criteria to accurately identify RLS and distinguish it from similar conditions.</p><p>3. Analyze the pharmacologic and non-pharmacologic treatment options to develop individualized RLS management plans.</p><p>4. Evaluate treatment responses and complications, including augmentation and adverse effects, to optimize ongoing care.</p><p><br></p><p><strong>INTENDED AUDIENCE</strong></p><p>This activity is intended for students, residents, primary care providers, internists, allied health, non-neurology specialists, and industry who have limited to no movement disorder experience.</p><p><br></p><p><strong>HARDWARE AND SOFTWARE REQUIREMENTS</strong></p><p>1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.</p><p>2. Compatible with Windows PC and MAC (256 MB of RAM or higher).</p><p>3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher.</p><p>4. Adobe Flash Player 12.0 (or higher).</p><p>5. Adobe Reader to print certificate.</p> 0 /Courses/Approach-and-Management-of-Restless-Legs-Syndrome.htm Approach and Management of Restless Legs Syndrome 2026-09-18T12:00:53.307 0 0 Foundational / Beginner Interactive CME English On-Demand Clinician Fellow Health Professional Industry Resident Student USA
Neurodegeneration with Brain Iron Accumulation
On Demand
Interactive
60 Minutes
Foundational / Beginner
CME Credits:1.001121 <span style="line-height:115%;">This course aims to provide you with a structured understanding of the approach and management of neurodegeneration with brain iron accumulation. Upon completion of this course, you will be able to discuss different types of neurodegeneration with brain iron accumulations, including age of onset, clinical manifestations, and genetics; differential diagnosis of neurodegeneration with brain iron accumulations and approach to diagnosis including imaging; as well as review treatment approaches in neurodegeneration with brain iron accumulations.</span> Biomarkers, Biomarkers & Diagnostic Tools, Cognitive impairment/Dementia, Genetic & Hereditary Disorders, Genetics, Medications for motor symptoms, Neuroimaging, Neuropathology, Non-motor Symptoms/Disorders, Other Movement Disorders, Physical Therapy/Physiotherapy, Rating Scales, Sensory disorders, Speech Disorders, Therapies-Other, Therapies-Pharmacological Susanne Schneider, MD, Soaham Desai, MD, DM 60 1.00 https://education.movementdisorders.org/Detail/1121/Neurodegeneration-with-Brain-Iron-Accumulation https://education.movementdisorders.org/Upload/ActivityImages/05INTERACT-47-001-Neurodegeneration-with-Brain-Iron-Accumulation--202x108626849.jpg https://education.movementdisorders.org/Upload/BannerImages/05INTERACT-47-001-Neurodegeneration-with-Brain-Iron-Accumulation-734x404812281.jpg 2026-08-21T00:00:00 2029-08-21T00:00:00 <p><strong>CREDIT DESIGNATION STATEMENT</strong></p><p>The International Parkinson and Movement Disorder Society designates this activity for a maximum of 1 <em>AMA PRA Category 1 Credits™</em>. Physicians should only claim credit commensurate with the extent of their participation.</p><p><br></p><p><strong>FACULTY DISCLOSURE</strong></p><p>All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available<a href="https://d1t84l7yt030ad.cloudfront.net/FroalaFiles/Final%20Disclosure%20Block_Neurodegeneration%20with%20Brain%20Iron%20Accumulation_14072026110011.pdf" rel="noopener noreferrer" target="_blank"> HERE</a>. All relevant financial relationships have been mitigated in advance of this program.</p><p><br></p><p><strong>SATISFACTORY COMPLETION</strong></p><p>Participants must complete an evaluation for each session they attend to receive continuing medical education credit. Your chosen session(s) must be attended in their entirety. Partial credit for individual sessions is not available.</p><p><br></p><p><strong>METHOD OF PARTICIPATION </strong></p><p>Your chosen sessions must be attended in their entirety. Partial credit of individual sessions is not available. If you are seeking continuing education credit for a specialty not listed in the Accreditation Statement, it is your responsibility to contact your licensing/certification board to determine course eligibility for your board requirement.</p><p><br></p><p><strong>CONTENT VALIDITY STATEMENT</strong></p><p>All recommendations involving clinical medicine in MDS activities are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the case of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendations conforms to the generally accepted standards of experimental design, data collection and analysis. Activities that promote recommendations, treatment or manners of practicing medicine not within the definition of CME or are knowing to have risks or dangers that outweigh the benefits or are knowing to be ineffective in the treatment of patients do not constitute valid CME.</p> MDS Education <p><span style="background-color: null;"><strong>FACULTY</strong></span></p><p><span style="background-color: null;">Susanne A. Schneider, MD - University Medical Center of the Johannes, Gutenberg University - Mainz, Germany</span></p><p><span style="background-color: null;">Soaham Desai, MD, DM - Shree Krishna Hospital, Pramukhswami Medical College, Bhaikaka University, Karamsad - Anand, Gujarat, India</span></p><p><br></p><p><strong>LEARNING OBJECTIVES</strong></p><p>Upon completion of this activity, learners will be able to: </p><p>1. Discuss different types of NBIA, including age of onset. clinical manifestations, and genetics</p><p>2. Discuss the differential diagnosis of NBIAs and approach to diagnosis, including imaging.</p><p>3. Review treatment approaches in NBIAs.</p><p><br></p><p><strong>INTENDED AUDIENCE</strong></p><p>This activity is intended for students, residents, primary care providers, internists, allied health, non-neurology specialists, and industry who have limited to no movement disorder experience.</p><p><br></p><p><strong>HARDWARE AND SOFTWARE REQUIREMENTS</strong></p><p>1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.</p><p>2. Compatible with Windows PC and MAC (256 MB of RAM or higher).</p><p>3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher.</p><p>4. Adobe Flash Player 12.0 (or higher).</p><p>5. Adobe Reader to print certificate.</p> 0 /Courses/Neurodegeneration-with-Brain-Iron-Accumulation.htm Neurodegeneration with Brain Iron Accumulation 2026-08-21T00:01:01.720 0 0 Foundational / Beginner Interactive CME On-Demand Clinician Fellow Health Professional Resident USA
Journal CME 41.08: Metabolic and Volumetric Alterations in the Basal Ganglia and the Cerebellum in Dopa-Responsive Dystonia in Symptomatic and Asymptomatic GCH1 Mutation Carriers
On Demand
Journal CME
60 Minutes
Experienced / Intermediate
CME Credits:1.001147 <p>The Journal CME 41.08 article aims to characterize the volumetric and neurometabolic brain changes in GCH1 mutation carriers (MC) and explore their relationship with clinical severity.</p> Basal Ganglia, Biomarkers, Biomarkers & Diagnostic Tools, Dystonia, Etiology & Pathophysiology, Genetics, Hyperkinetic Movement Disorders, Neuroimaging, Neuropathology, Rating Scales Jannik Prasuhn, MD 60 1.00 https://education.movementdisorders.org/Detail/1147/Journal-CME-41-08:-Metabolic-and-Volumetric-Alterations-in-the-Basal-Ganglia-and-the-Cerebellum-in-Dopa-Responsive-Dystonia-in-Symptomatic-and-Asymptomatic-GCH1-Mutation-Carriers https://education.movementdisorders.org/Upload/ActivityImages/Journal-CME562837664663.jpg 2026-08-14T00:00:00 2027-08-14T00:00:00 <p><strong>ACCREDITATION STATEMENT</strong></p><p>This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME). The International Parkinson and Movement Disorder Society is accredited by the ACCME to provide continuing medical education for physicians.</p><p><br></p><p><strong>CREDIT DESIGNATION STATEMENT</strong></p><p>The International Parkinson and Movement Disorder Society designates this activity for a maximum of 1 <em>AMA PRA Category 1 Credits™</em>. Physicians should only claim credit commensurate with the extent of their participation.</p><p><br></p><p><strong>FACULTY DISCLOSURE</strong></p><p>All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available <a href="https://d1t84l7yt030ad.cloudfront.net/FroalaFiles/Journal%20CME%2041.08%20-%20Disclosures_12082026085638.pdf" rel="noopener noreferrer" target="_blank"><u>HERE</u></a>. All relevant financial relationships have been mitigated in advance of this program.</p><p><br></p><p><strong>METHOD OF PARTICIPATION</strong></p><p>Each module will take approximately one (1) hour to complete. Upon reading the article, participants will take a post-test and must receive a grade of 75% or higher to pass. Participants are allowed multiple attempts to complete the post-test. Once the post-test is passed, participants are required to complete the module evaluation.</p><p><br></p><p><strong>SATISFACTORY COMPLETION</strong></p><p>Participants must complete an evaluation for each session they attend to receive continuing medical education credit. Your chosen session(s) must be attended in their entirety. Partial credit for individual sessions is not available.</p><p><br></p><p><strong>CONTENT VALIDITY STATEMENT</strong></p><p>All recommendations involving clinical medicine in MDS activities are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the case of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendations conforms to the generally accepted standards of experimental design, data collection and analysis. Activities that promote recommendations, treatment or manners of practicing medicine not within the definition of CME or are knowing to have risks or dangers that outweigh the benefits or are knowing to be ineffective in the treatment of patients do not constitute valid CME.</p> MDS Education <p><strong>COURSE PURPOSE</strong></p><p>Journal CME highlights various articles covering relevant issues, developments and research topics in the area of movement disorders. Articles are selected from Movement Disorders, the official Journal of the International Parkinson and Movement Disorder Society.</p><p><br></p><p><strong>LEARNING OBJECTIVES</strong></p><p>Upon completion of this activity, learners will be able to:</p><p>1. Understand the role of GCH1 and tetrahydrobiopterin in dopamine synthesis</p><p>2. Assess the clinical and imaging methods used to characterize GCH1-related DRD</p><p>3. Evaluate structural and metabolic changes in the basal ganglia and cerebellum associated with GCH1-related DRD</p><p><br></p><p><strong>INTENDED AUDIENCE</strong></p><p>This activity is intended for clinicians, other health professionals, researchers, policy makers from throughout the world, both MDS members and non-members, who interact with patients living with Movement Disorders.</p><p><br></p><p><strong>HARDWARE AND SOFTWARE REQUIREMENTS</strong></p><p>1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.</p><p>2. Compatible with Windows PC and MAC (256 MB of RAM or higher).</p><p>3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher.</p><p>4. Adobe Flash Player 12.0 (or higher).</p><p>5. Adobe Reader to print certificate.</p> 0 /Courses/Journal-CME-41.08-Metabolic-and-Volumetric-Alterations-in-the-Basal-Ganglia-and-the-Cerebellum-in-Dopa-Responsive-Dystonia-in-Symptomatic-and-Asymptomatic-GCH1-Mutation-Carriers.htm Journal CME 41.08: Metabolic and Volumetric Alterations in the Basal Ganglia and the Cerebellum in Dopa-Responsive Dystonia in Symptomatic and Asymptomatic GCH1 Mutation Carriers Journal CME 41.08 2026-08-14T18:00:53.077 0 0 Experienced / Intermediate Journal CME CME English On-Demand Clinician Fellow Industry Researcher Resident USA
Exercise and Physical Activity for Patients with Parkinson's Disease
On Demand
Interactive
60 Minutes
Foundational / Beginner
CME Credits:1.001132 <span style="line-height:107%;">The module summarizes the definition of exercise and physical activities as well as their general health-related benefits in healthy adults. Following upon that, the evidence for the effect of specific types of exercise and physical activities as a symptomatic treatment in Parkinson’s disease is presented. Finally, the potential disease-modifying role of exercise and physical activities is discussed. </span> Exercise, Parkinson Disease/Hypokinetic Movement Disorders, Parkinson's Disease (PD), Physical Therapy/Physiotherapy, Therapies-Other Miriam R. Rafferty, DPT, Phd, Mitra Rouhani, PhD, MSPT, BSPT 60 1.00 https://education.movementdisorders.org/Detail/1132/Exercise-and-Physical-Activity-for-Patients-with-Parkinson's-Disease https://education.movementdisorders.org/Upload/ActivityImages/05INTERACT-46-001-Exercise-for-PD-202x108347160.jpg https://education.movementdisorders.org/Upload/BannerImages/05INTERACT-46-001-Exercise-for-PD-734x404863637.jpg 2026-07-22T00:00:00 2029-07-22T00:00:00 <p><strong>CREDIT DESIGNATION STATEMENT</strong></p><p>The International Parkinson and Movement Disorder Society designates this activity for a maximum of 1 <em>AMA PRA Category 1 Credits™</em>. Physicians should only claim credit commensurate with the extent of their participation.</p><p><br></p><p><strong>FACULTY DISCLOSURE</strong></p><p>All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available <a href="https://d1t84l7yt030ad.cloudfront.net/FroalaFiles/Final%20Disclosure%20Block_Exercise%20&%20Physical%20Activity%20for%20Patients%20with%20MD_21072026014322.pdf">HERE</a>. All relevant financial relationships have been mitigated in advance of this program.</p><p><br></p><p><strong>SATISFACTORY COMPLETION</strong></p><p>Participants must complete an evaluation for each session they attend to receive continuing medical education credit. Your chosen session(s) must be attended in their entirety. Partial credit for individual sessions is not available.</p><p><br></p><p><strong>METHOD OF PARTICIPATION </strong></p><p>Your chosen sessions must be attended in their entirety. Partial credit of individual sessions is not available. If you are seeking continuing education credit for a specialty not listed in the Accreditation Statement, it is your responsibility to contact your licensing/certification board to determine course eligibility for your board requirement.</p><p><br></p><p><strong>CONTENT VALIDITY STATEMENT</strong></p><p>All recommendations involving clinical medicine in MDS activities are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the case of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendations conforms to the generally accepted standards of experimental design, data collection and analysis. Activities that promote recommendations, treatment or manners of practicing medicine not within the definition of CME or are knowing to have risks or dangers that outweigh the benefits or are knowing to be ineffective in the treatment of patients do not constitute valid CME.</p> MDS Education <p><span style="background-color: null;"><strong>FACULTY</strong></span></p><p><span style="background-color: null;">Miriam Rafferty, DPT, PhD - Northwestern University - Evanston, Illinois, USA</span></p><p><span style="background-color: null;">Mitra Rouhani, PhD, MSPT, BSPT - Northwestern University - Evanston, Illinois, USA</span></p><p><br></p><p><strong>LEARNING OBJECTIVES</strong></p><p>Upon completion of this activity, learners will be able to: </p><p>1. Understand the rationale behind using exercise and physical activities as a treatment option in Parkinson's disease</p><p>2. Learn about specific types of exercise and physical activities that can be used in Parkinson's disease</p><p>3. Gain insight into the current state of the debate about the potential disease modifying effect of exercise and physical activity.</p><p><br></p><p><strong>INTENDED AUDIENCE</strong></p><p>This activity is intended for students, residents, primary care providers, internists, allied health, non-neurology specialists, and industry who have limited to no movement disorder experience.</p><p><br></p><p><strong>HARDWARE AND SOFTWARE REQUIREMENTS</strong></p><p>1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.</p><p>2. Compatible with Windows PC and MAC (256 MB of RAM or higher).</p><p>3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher.</p><p>4. Adobe Flash Player 12.0 (or higher).</p><p>5. Adobe Reader to print certificate.</p> 0 /Courses/Exercise-and-Physical-Activity-for-Patients-with-Parkinsons-Disease.htm Exercise and Physical Activity for Patients with Parkinson's Disease 2026-07-22T00:01:00.333 0 0 Foundational / Beginner Interactive CME English On-Demand Clinician Clinician-General Neurologist Clinician-Movement Disorder Specialist Clinician-Other Clinician-Primary Care Clinician-Researcher Fellow Fellow-Clinical Fellow-Clinical Research Fellow-Movement Disorders Fellow-Other (Post Doc) Health Professional Health Professional-Clinical Nurse Specialist Health Professional-Dieticians Health Professional-Nurse Health Professional-Nurse Practitioner Health Professional-Occupational Health Professional-Other Health Professional-Physician Assistants Health Professional-Physio / Physical Health Professional-Psychologists Health Professional-Therapist Resident Resident-Neurology Resident-Other Retired Retired-Clinician/Faculty Retired-Health Professional Student Student-Graduate Student-Medical Student-Undergraduate USA
Journal CME 41.07: Automating Subthalamic Deep Brain Stimulation Programming with Evoked Resonant Neural Activity in Parkinson’s Disease
On Demand
Journal CME
60 Minutes
Experienced / Intermediate
CME Credits:1.001128 <p>The Journal CME 41.07 article aims to investigate the feasibility and acute motor benefit of STN-DBS programming, guided by intraoperatively recorded evoked resonant neural activity (ERNA) in patients with PD.</p> Deep brain stimulation, Parkinson Disease/Hypokinetic Movement Disorders, Parkinson's Disease (PD), Therapies-Surgical Kanae J. Nagao, MBBS, FRACP 60 1.00 https://education.movementdisorders.org/Detail/1128/Journal-CME-41-07:-Automating-Subthalamic-Deep-Brain-Stimulation-Programming-with-Evoked-Resonant-Neural-Activity-in-Parkinson’s-Disease https://education.movementdisorders.org/Upload/ActivityImages/Journal-CME562837664663.jpg 2026-06-30T00:00:00 2027-06-30T00:00:00 <p><strong>ACCREDITATION STATEMENT</strong></p><p>This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME). The International Parkinson and Movement Disorder Society is accredited by the ACCME to provide continuing medical education for physicians.</p><p><br></p><p><strong>CREDIT DESIGNATION STATEMENT</strong></p><p>The International Parkinson and Movement Disorder Society designates this activity for a maximum of 1 <em>AMA PRA Category 1 Credits™</em>. Physicians should only claim credit commensurate with the extent of their participation.</p><p><br></p><p><strong>FACULTY DISCLOSURE</strong></p><p>All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available <a href="https://d1t84l7yt030ad.cloudfront.net/FroalaFiles/Journal%20CME%2041.07%20-%20Disclosures_30062026101221.pdf" rel="noopener noreferrer" target="_blank"><u>HERE</u></a>. All relevant financial relationships have been mitigated in advance of this program.</p><p><br></p><p><strong>METHOD OF PARTICIPATION</strong></p><p>Each module will take approximately one (1) hour to complete. Upon reading the article, participants will take a post-test and must receive a grade of 75% or higher to pass. Participants are allowed multiple attempts to complete the post-test. Once the post-test is passed, participants are required to complete the module evaluation.</p><p><br></p><p><strong>SATISFACTORY COMPLETION</strong></p><p>Participants must complete an evaluation for each session they attend to receive continuing medical education credit. Your chosen session(s) must be attended in their entirety. Partial credit for individual sessions is not available.</p><p><br></p><p><strong>CONTENT VALIDITY STATEMENT</strong></p><p>All recommendations involving clinical medicine in MDS activities are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the case of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendations conforms to the generally accepted standards of experimental design, data collection and analysis. Activities that promote recommendations, treatment or manners of practicing medicine not within the definition of CME or are knowing to have risks or dangers that outweigh the benefits or are knowing to be ineffective in the treatment of patients do not constitute valid CME.</p> MDS Education <p><strong>COURSE PURPOSE</strong></p><p>Journal CME highlights various articles covering relevant issues, developments and research topics in the area of movement disorders. Articles are selected from Movement Disorders, the official Journal of the International Parkinson and Movement Disorder Society.</p><p><br></p><p><strong>LEARNING OBJECTIVES</strong></p><p>Upon completion of this activity, learners will be able to:</p><p>1. Understand the role of evoked resonant neural activity (ERNA) in deep brain stimulation programming<br>2. Assess the clinical performance of ERNA-guided programming compared with conventional programming methods<br>3. Evaluate the potential of ERNA-guided programming to improve deep brain stimulation outcomes in Parkinson's disease</p><p><br></p><p><strong>INTENDED AUDIENCE</strong></p><p>This activity is intended for clinicians, other health professionals, researchers, policy makers from throughout the world, both MDS members and non-members, who interact with patients living with Movement Disorders.</p><p><br></p><p><strong>HARDWARE AND SOFTWARE REQUIREMENTS</strong></p><p>1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.</p><p>2. Compatible with Windows PC and MAC (256 MB of RAM or higher).</p><p>3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher.</p><p>4. Adobe Flash Player 12.0 (or higher).</p><p>5. Adobe Reader to print certificate.</p> 0 /Courses/Journal-CME-41.07-Automating-Subthalamic-Deep-Brain-Stimulation-Programming-with-Evoked-Resonant-Neural-Activity-in-Parkinsons-Disease.htm Journal CME 41.07: Automating Subthalamic Deep Brain Stimulation Programming with Evoked Resonant Neural Activity in Parkinson’s Disease Journal CME 41.07 2026-06-30T12:00:55.333 0 0 Experienced / Intermediate Journal CME CME English On-Demand Clinician Fellow Industry Researcher Resident USA
Journal CME 41.06: An Open-Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington’s Disease
On Demand
Journal CME
60 Minutes
Experienced / Intermediate
CME Credits:1.001127 <p>The Journal CME 41.06 article aims to eassess the safety, pharmacokinetics (PK), pharmacodynamics, and clinical activity of ANX005 in patients with Huntington’s disease (HD).</p> Chorea/Huntingtons Disease (HD), Clinical Trials, Hyperkinetic Movement Disorders, Therapies-Pharmacological Rajeev Kumar, MD 60 1.00 https://education.movementdisorders.org/Detail/1127/Journal-CME-41-06:-An-Open-Label-Phase-1b-Study-of-the-Safety,-Pharmacokinetics,-Pharmacodynamics,-and-Clinical-Activity-of-ANX005-in-Patients-with-Huntington’s-Disease https://education.movementdisorders.org/Upload/ActivityImages/Journal-CME562837664663.jpg 2026-06-30T00:00:00 2027-06-30T00:00:00 <p><strong>ACCREDITATION STATEMENT</strong></p><p>This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME). The International Parkinson and Movement Disorder Society is accredited by the ACCME to provide continuing medical education for physicians.</p><p><br></p><p><strong>CREDIT DESIGNATION STATEMENT</strong></p><p>The International Parkinson and Movement Disorder Society designates this activity for a maximum of 1 <em>AMA PRA Category 1 Credits™</em>. Physicians should only claim credit commensurate with the extent of their participation.</p><p><br></p><p><strong>FACULTY DISCLOSURE</strong></p><p>All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available <a href="https://d1t84l7yt030ad.cloudfront.net/FroalaFiles/Journal%20CME%2041.06%20-%20Disclosures_30062026092726.pdf" rel="noopener noreferrer" target="_blank"><u>HERE</u></a>. All relevant financial relationships have been mitigated in advance of this program.</p><p><br></p><p><strong>METHOD OF PARTICIPATION</strong></p><p>Each module will take approximately one (1) hour to complete. Upon reading the article, participants will take a post-test and must receive a grade of 75% or higher to pass. Participants are allowed multiple attempts to complete the post-test. Once the post-test is passed, participants are required to complete the module evaluation.</p><p><br></p><p><strong>SATISFACTORY COMPLETION</strong></p><p>Participants must complete an evaluation for each session they attend to receive continuing medical education credit. Your chosen session(s) must be attended in their entirety. Partial credit for individual sessions is not available.</p><p><br></p><p><strong>CONTENT VALIDITY STATEMENT</strong></p><p>All recommendations involving clinical medicine in MDS activities are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the case of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendations conforms to the generally accepted standards of experimental design, data collection and analysis. Activities that promote recommendations, treatment or manners of practicing medicine not within the definition of CME or are knowing to have risks or dangers that outweigh the benefits or are knowing to be ineffective in the treatment of patients do not constitute valid CME.</p> MDS Education <p><strong>COURSE PURPOSE</strong></p><p>Journal CME highlights various articles covering relevant issues, developments and research topics in the area of movement disorders. Articles are selected from Movement Disorders, the official Journal of the International Parkinson and Movement Disorder Society.</p><p><br></p><p><strong>LEARNING OBJECTIVES</strong></p><p>Upon completion of this activity, learners will be able to:</p><p>1. Understand the role of complement inhibition in Huntington's disease</p><p>2. Assess the safety and preliminary clinical findings of ANX005</p><p>3. Evaluate the potential role of complement biomarkers in guiding Huntington's disease treatment</p><p><br></p><p><strong>INTENDED AUDIENCE</strong></p><p>This activity is intended for clinicians, other health professionals, researchers, policy makers from throughout the world, both MDS members and non-members, who interact with patients living with Movement Disorders.</p><p><br></p><p><strong>HARDWARE AND SOFTWARE REQUIREMENTS</strong></p><p>1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.</p><p>2. Compatible with Windows PC and MAC (256 MB of RAM or higher).</p><p>3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher.</p><p>4. Adobe Flash Player 12.0 (or higher).</p><p>5. Adobe Reader to print certificate.</p> 0 /Courses/Journal-CME-41.06-An-Open-Label-Phase-1b-Study-of-the-Safety-Pharmacokinetics-Pharmacodynamics-and-Clinical-Activity-of-ANX005-in-Patients-with-Huntingtons-Disease.htm Journal CME 41.06: An Open-Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington’s Disease Journal CME 41.06 2026-06-30T12:00:53.910 0 0 Experienced / Intermediate Journal CME CME English On-Demand Clinician Fellow Industry Researcher Resident USA
Palliative Care in Movement Disorders
On Demand
Interactive
60 Minutes
Foundational / Beginner
CME Credits:1.001119 <span style="line-height:107%;">This module provides an in-depth knowledge about approaches to achieve holistic palliative care in Movement Disorders. The module gives an overview of pharmacological and non-pharmacological approaches used in palliative medicine for patients with Movement Disorders and outlines different strategies to support patients and care partners.</span> Care Models, Palliative care and Hospice Veronica Bruno, MD, MPH 60 1.00 https://education.movementdisorders.org/Detail/1119/Palliative-Care-in-Movement-Disorders https://education.movementdisorders.org/Upload/ActivityImages/05INTERACT-48-001-Palliative-care-202x108908985.jpg https://education.movementdisorders.org/Upload/BannerImages/05INTERACT-48-001-Palliative-care-734x404391847.jpg 2026-06-17T00:00:00 2029-06-17T00:00:00 <p><strong>ACCREDITATION STATEMENT</strong></p><p>This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME). The International Parkinson and Movement Disorder Society is accredited by the ACCME to provide continuing medical education for physicians.</p><p><br></p><p><strong>CREDIT DESIGNATION STATEMENT</strong></p><p>The International Parkinson and Movement Disorder Society designates this activity for a maximum of 1 <em>AMA PRA Category 1 Credits™</em>. Physicians should only claim credit commensurate with the extent of their participation.</p><p><br></p><p><strong>FACULTY DISCLOSURE</strong></p><p>All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available <a href="https://d1t84l7yt030ad.cloudfront.net/FroalaFiles/Final%20Disclosure%20Block_Palliative%20Care%20in%20Movement%20Disorders_17062026092124.pdf" rel="noopener noreferrer" target="_blank">HERE</a>. All relevant financial relationships have been mitigated in advance of this program.</p><p><br></p><p><strong>SATISFACTORY COMPLETION</strong></p><p>Participants must complete an evaluation for each session they attend to receive continuing medical education credit. Your chosen session(s) must be attended in their entirety. Partial credit for individual sessions is not available.</p><p><br></p><p><strong>METHOD OF PARTICIPATION </strong></p><p>Your chosen sessions must be attended in their entirety. Partial credit of individual sessions is not available. If you are seeking continuing education credit for a specialty not listed in the Accreditation Statement, it is your responsibility to contact your licensing/certification board to determine course eligibility for your board requirement.</p><p><br></p><p><strong>CONTENT VALIDITY STATEMENT</strong></p><p>All recommendations involving clinical medicine in MDS activities are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the case of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendations conforms to the generally accepted standards of experimental design, data collection and analysis. Activities that promote recommendations, treatment or manners of practicing medicine not within the definition of CME or are knowing to have risks or dangers that outweigh the benefits or are knowing to be ineffective in the treatment of patients do not constitute valid CME.</p> MDS Education <p><span style="background-color: null;"><strong>FACULTY</strong></span></p><p>Veronica Bruno, MD, MPH - University of Calgary, Calgary, Canada</p><p><br></p><p><strong>LEARNING OBJECTIVES</strong></p><p>Upon completion of this activity, learners will be able to: </p><p>1. Identify the importance of palliative care in movement disorders.</p><p>2. Structure a comprehensive pallaitive care consultation.</p><p>3. Identify and manage common challenges in advanced movement disorders.</p><p><br></p><p><strong>INTENDED AUDIENCE</strong></p><p>This activity is intended for students, residents, primary care providers, internists, allied health, non-neurology specialists, and industry who have limited to no movement disorder experience.</p><p><br></p><p><strong>HARDWARE AND SOFTWARE REQUIREMENTS</strong></p><p>1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.</p><p>2. Compatible with Windows PC and MAC (256 MB of RAM or higher).</p><p>3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher.</p><p>4. Adobe Flash Player 12.0 (or higher).</p><p>5. Adobe Reader to print certificate.</p> 0 /Courses/Palliative-Care-in-Movement-Disorders.htm Palliative Care in Movement Disorders 2026-06-17T12:01:11.990 0 0 Foundational / Beginner Interactive CME English On-Demand Clinician Clinician-General Neurologist Clinician-Movement Disorder Specialist Clinician-Other Clinician-Primary Care Clinician-Researcher Fellow Fellow-Clinical Fellow-Movement Disorders Health Professional Health Professional-Clinical Nurse Specialist Health Professional-Dieticians Health Professional-Music Health Professional-Nurse Health Professional-Nurse Practitioner Health Professional-Occupational Health Professional-Other Health Professional-Physician Assistants Health Professional-Physio / Physical Health Professional-Psychologists Health Professional-Social Work Health Professional-Speech Health Professional-Therapist Resident Resident-Neurology Resident-Other Student-Medical USA
Journal CME 41.05: Perampanel Blocks Transsynaptic a-Synuclein Propagation and Neurodegeneration in a Mouse Model of Lewy Body Disease
On Demand
Journal CME
60 Minutes
Experienced / Intermediate
CME Credits:1.001120 <p>The Journal CME 41.05 article aims to elucidate the underlying mechanisms of this effect and whether perampanel inhibits transsynaptic α-synuclein propagation.</p> Basic/Translational Neuroscience, Etiology & Pathophysiology, Lewy-body dementia (LBD), Medications for motor symptoms, Medications for non-motor symptoms, Parkinson Disease/Hypokinetic Movement Disorders, Parkinson's Disease (PD), Synucleinopathy, Therapies-Pharmacological Jun Ueda, MD, PhD 60 1.00 https://education.movementdisorders.org/Detail/1120/Journal-CME-41-05:-Perampanel-Blocks-Transsynaptic-a-Synuclein-Propagation-and-Neurodegeneration-in-a-Mouse-Model-of-Lewy-Body-Disease https://education.movementdisorders.org/Upload/ActivityImages/Journal-CME562837664663.jpg 2026-06-05T00:00:00 2027-06-05T00:00:00 <p><strong>ACCREDITATION STATEMENT</strong></p><p>This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME). The International Parkinson and Movement Disorder Society is accredited by the ACCME to provide continuing medical education for physicians.</p><p><br></p><p><strong>CREDIT DESIGNATION STATEMENT</strong></p><p>The International Parkinson and Movement Disorder Society designates this activity for a maximum of 1 <em>AMA PRA Category 1 Credits™</em>. Physicians should only claim credit commensurate with the extent of their participation.</p><p><br></p><p><strong>FACULTY DISCLOSURE</strong></p><p>All individuals in control of content for this activity are required to disclose all financial relationships with ineligible companies (as defined by the ACCME) over the last 24 months. Disclosure information is available <a href="https://d1t84l7yt030ad.cloudfront.net/FroalaFiles/Journal%20CME%2041.05%20-%20Disclousers_04062026015555.pdf" rel="noopener noreferrer" target="_blank"><u>HERE</u></a>. All relevant financial relationships have been mitigated in advance of this program.</p><p><br></p><p><strong>METHOD OF PARTICIPATION</strong></p><p>Each module will take approximately one (1) hour to complete. Upon reading the article, participants will take a post-test and must receive a grade of 75% or higher to pass. Participants are allowed multiple attempts to complete the post-test. Once the post-test is passed, participants are required to complete the module evaluation.</p><p><br></p><p><strong>SATISFACTORY COMPLETION</strong></p><p>Participants must complete an evaluation for each session they attend to receive continuing medical education credit. Your chosen session(s) must be attended in their entirety. Partial credit for individual sessions is not available.</p><p><br></p><p><strong>CONTENT VALIDITY STATEMENT</strong></p><p>All recommendations involving clinical medicine in MDS activities are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the case of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendations conforms to the generally accepted standards of experimental design, data collection and analysis. Activities that promote recommendations, treatment or manners of practicing medicine not within the definition of CME or are knowing to have risks or dangers that outweigh the benefits or are knowing to be ineffective in the treatment of patients do not constitute valid CME.</p> MDS Education <p><strong>COURSE PURPOSE</strong><br>Journal CME highlights various articles covering relevant issues, developments and research topics in the area of movement disorders. Articles are selected from Movement Disorders, the official Journal of the International Parkinson and Movement Disorder Society.<br><strong><br>LEARNING OBJECTIVES</strong><br>Upon completion of this activity, learners will be able to:<br>1. Understand the role of transsynaptic α-synuclein propagation and dynamin-dependent endocytosis in the progression of Lewy body disease<br>2. Assess the effects of perampanel on α-synuclein uptake, pathology spread, and neurodegeneration in preclinical models<br>3. Evaluate the potential of perampanel as a disease-modifying therapeutic strategy for Lewy body disease<br><strong><br>INTENDED AUDIENCE</strong><br>This activity is intended for clinicians, other health professionals, researchers, policy makers from throughout the world, both MDS members and non-members, who interact with patients living with Movement Disorders.<br><br><strong>HARDWARE AND SOFTWARE REQUIREMENTS</strong><br>1. Active Internet connection (DSL or Cable). Dial-up connection will have constant buffering problem.<br>2. Compatible with Windows PC and MAC (256 MB of RAM or higher).<br>3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 29.0 or higher.<br>4. Adobe Flash Player 12.0 (or higher).<br>5. Adobe Reader to print certificate.</p> 0 /Courses/Journal-CME-41.05-Perampanel-Blocks-Transsynaptic-a-Synuclein-Propagation-and-Neurodegeneration-in-a-Mouse-Model-of-Lewy-Body-Disease.htm Journal CME 41.05: Perampanel Blocks Transsynaptic a-Synuclein Propagation and Neurodegeneration in a Mouse Model of Lewy Body Disease Journal CME 41.05 2026-06-08T09:01:13.170 0 0 Experienced / Intermediate Journal CME CME English On-Demand Clinician Fellow Industry Researcher Resident USA
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