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International Parkinson and Movement Disorder Society
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Normal Pressure Hydrocephalus (NPH) Study Group

Alfonso Fasano
Joachim Krauss

Joachim Krauss
Alfonso Fasano

MDS Staff Liaison: Maddy Kolb

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Alberto Espay, University of Cincinnati, USA

Alessandro Tessitore, University of Campania Luigi Vanvitelli, Italy

Alissa Higinbotham, University of Virginia Medical Center, USA 

Amtul Farheen, Lebanon VA Medical Center, USA

Anders Eklund, University of Umea, Sweden

Andrea Quattrone, University Magna Graecia of Catanzaro, Italy

Andy Parrent, University of Western Ontario, Canada

Anthony E. Lang, University of Toronto, Canada

Araceli Alonso Canovas, Hospital Ramón y Cajal, Spain

Bastiaan R. Bloem, Radboud University, the Netherlands

Bettina Balint, University Hospital Zurich, Switzerland 

Brent R. Bluett, Stanford Movement Disorders Center, USA

Camilla Kilbane, University Hospital Cleveland Medical Center, USA 

Carmela Tartaglia, University of Toronto, Canada

Carsten Wikkelso, Sahlgrenska University Hospital, Sweden

Christopher W. Hess, Norman Fixel Institute for Neurological Diseases, USA

Christos Sidiropoulos, Michigan State University, USA

Claudio Pacchetti, Istituto Mondino, Italy

David Campo-Caballero, Donostia University Hospital, Spain 

David Tang-Wai, University of Toronto, Canada

Davide Martino, Calgary University, Canada

Elissa Ash, Tel Aviv Medical Center, Israel

Erik H. Middlebrooks, Mayo Clinic, USA

Gabor G. Kovacs, University of Toronto, Canada 

George R. Wilmot, Emory University, USA

Giovanni Mostile, University of Catania, Italy

Greydon Gilmore, Western University, Canada

Hrishikesh Kumar, Institute of Neurosciences, Kolkata, India

Iciar Aviles Olmos, Clinica Universidad de Navarra, Spain 

Jan Malm, University of Umea, Sweden

Jay A van Gerpen, National Institute of Neurological Disorders, USA

Jinyoung Youn, Samsung Medical Center, South Korea

Katarzyna Smilowska, Radboud University Medical Center, Poland

Klaus Jahn, LMU Munich and Schoen Clinic Bad Aibling, Germany 

Lealani Mae Acosta, Vanderbilt University Medical Center, USA

Lennart Stieglitz, Universitäts Spital Zürich, Switzerland

Louis Verret, Centre Pôle Santé Sud, Canada

Marco Fontanella, University of Brescia, Italy

Marie Laure Welter, CHU Rouen, France 

Mario Zappia, University of Catania, Italy

Mark Hamilton, University of Calgary, Canada

Massimiliano Todisco, IRCCS Mondino Foundation, Italy

Michael A. Williams, University of Washington, USA

Michael R. Silver, Emory University Hospital, USA

Michele Tinazzi, University of Verona, Italy

Mwiza Ushe, Washington University School of Medicine, USA

Natividad P. Stover, University of Alabama at Birmingham, USA

Neha Prakash, University of Connecticut, USA

Neil Mahant, Westmead Hospital, Australia

Neill Graff-Radford, Mayo Clinic Jacksonville, USA

Padraig O'Suilleabhain, Southwestern Medical Center, USA

Petra Klinge, The Warren Alpert Medical School of Brown University, USA

Pier Paolo Panciani, University of Brescia, Italy

Philippe Rizek, University of Toronto, Canada

Phillip Tipton, Mayo Clinic, USA

Rahil Ansari, Seth GSMC and KEM Hospital, India

Rhonna Shatz , University of Cincinnati, USA

Roberto Ceravolo, University of Pisa, Italy

Sean Nagel, Cleveland Clinic, USA

Sergiu Groppa, University Medical Center of the Johannes Gutenberg University Mainz, Germany 

Taiji Tsunemi, Northwestern University, USA

Victor Fung, University of Sydney, Australi

Vijayashankar Paramanandam, Apollo Hospital, India 


Normal Pressure Hydrocephalus (NPH) is a still obscure condition, relatively frequent but historically not addressed by Movement Disorders (MDS) publications or conferences. Most patients with NPH present with gait disorders at onset (often in isolation) and often the differential diagnosis includes Parkinson's disease, progressive supranuclear palsy or higher level gait disorders caused by vascular brain diseases. Recently, the pathophysiology and real existence of NPH has been questioned, thus starting a debate among NPH experts and movement disorders neurologists. For these reasons the time has come for the International Parkinson and Movement Disorder Society (MDS) to establish a study group on NPH.

Unmet Needs

  • Lack of standardized assessments to inform diagnosis and differential diagnosis (e.g. gold standard for procedures such as transient CSF shunting – tap tests or external lumbar drainage, neuroimaging, gait analysis, etc.)
  • Lack of collaborative research efforts
  • Lack of defined research goals (e.g. role of CSF biomarkers, surgical outcome predictors, pathological findings, double-blind clinical trials)
  • Lack of communication between IPDMDS and other societies

The study group will function as a ‘round table’ for neurologists with interest in phenomenology (particularly gait and balance), neuropsychologists, neurosurgeons as well as scientists involved in neurodegenerative diseases. Particular attention will be given to aspects related to our field of movement disorders, such type of freezing of gait displayed by NPH patients, clinical and pathophysiological meaning of L-dopa responsiveness or abnormal dopamine imaging. The study group is open to considering new members interested in NPH.


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Published Papers

Published paper

Clinical Features of Idiopathic Normal Pressure Hydrocephalus: Critical Review of Objective Finding

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Resource Type
  • Published paper
Authoring group
  • Normal Pressure Hydrocephalus (NPH)

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