MDS Non-Motor Rating Scale (MDS-NMS)

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The International Parkinson and Movement Disorder Society – Non-Motor Rating Scale


Acronym: MDS-NMS

Authors: K. Ray Chaudhuri, Anette Schrag, Daniel Weintraub, Alexandra Rizos, Carmen Rodriguez-Blazquez, Eugenia Mamikonyan and Pablo Martinez-Martin

The MDS-NMS is a revision of the Non-Motor Symptoms Scale (NMSS) and was developed to improve and refine the assessment of non-motor symptoms in Parkinson’s disease (PD). This rater-completed assessment measures frequency and severity of 13 non-motor domains, over 52 items and covers a range of key non-motor symptoms both PD and treatment related, and in greater depth, compared with the NMSS. The scale also has a new MDS-NMS Non-Motor Fluctuations (NMF) Subscale to assess changes in non-motor symptoms in relation to the timing of anti-parkinsonian medications across 8 domains.

This scale is expected to be useful in clinical care and research, including trials of investigational medicinal products related to PD. The MDS-NMS is a valid and reliable rating scale that measures the burden of non-motor symptoms, including non-motor fluctuations, in PD patients.

Original PublicationView the Scale (PDF)

Year Published: 2019

Estimated Time to Complete: The estimated time for completion of the scale is 15-40 minutes, depending on the status of patient and number of non-motor symptoms present.

Assessment Type: ClinRO

Additional Scale Publications:

Martinez-Martin P, Schrag A, Weintraub D, Rizos A, Rodriquez-Blazquez C, Chaudhuri KR. Pilot Study of the International Parkinson and Movement Disorder Society-Sponsored Non-motor Rating Scale (MDS-NMS). Movement Disorders Clinical Practice. 2019 Jan;6(3):227-234.


Martinez‐Martin, P., Rojo‐Abuín, J. M., Weintraub, D., Chaudhuri, K. R., Rodriguez‐Blázquez, C., Rizos, A., & Schrag, A. Factor Analysis and Clustering of the Movement Disorder Society–Non‐Motor Rating Scale. Movement Disorders Movement Disorders, 35(6):969–975. June 2020.

Chaudhuri, K. R., Schrag, A., Weintraub, D., Rizos, A., Rodriguez‐Blazquez, C., Mamikonyan, E., & Martinez‐Martin, P. Chaudhuri, K. R., Schrag, A., Weintraub, D., Rizos, A., Rodriguez‐Blazquez, C., Mamikonyan, E., & Martinez‐Martin, P. Movement Disorders, 35(1):116–133. January 2020. Movement Disorders, 35(1):116–133. January 2020.

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