Quantitative Measurements of α-Synuclein Seeds in Cerebrospinal Fluid Inform Diagnosis and Staging of Synucleinopathies

How can biological assays for diagnosis of α-synucleinopathies be improved? This study led by Dr. Omar El-Agnaf introduced a seeding amplification immunoassay (SAIA) that adds a quantitative measurement transferable to the clinical setting. This highlighted research was presented during the 2024 International Congress of Parkinson’s Disease and Movement Disorders (mdscongress.org). Authors: O. El-Agnaf
I. Abdi
I. Sudhakaran
S. Ghanem
V. Constantinides
E. Kapaki
W. van de Berg
D. Erskine
B. Mollenhauer
L. Parkkinen
M. Schlossmacher (Ar Rayyan, Qatar). Funded by the Qatar National Research Fund. Read the full abstract at mdsabstracts.org.