MDS Non-Motor Symptoms - Questionnaire (MDS-NMS-Q)
Permission is required for each single use of the MDS Clinical Outcome Assessments.
The MDS-NMS-Q is a self-completed, simplified (focusing on severity only) questionnaire version of the rater-administered MDS-NMS, developed and validated for use in Parkinson’s disease (PD).
The main instrument of the MDS-NMS-Q is a 13-domain, 52-item instrument covering the most commonly-reported non-motor symptoms in Parkinson’s disease. There is also a separate, non-motor fluctuations (NMFs) subscale covering 8 commonly-reported NMFs occurring in the context of PD medication wearing “off” periods. In the validation study, data quality was satisfactory for all 13 MDS-NMS-Q domains. There were no floor or ceiling effects for the total score; individual domains had no appreciable ceiling effects but variable floor effects. Internal consistency for most domains was satisfactory, except for the impulse control domain. Correlation and concordance between MDS-NMS-Q and MDS-NMS total scores were high. Thus, the MDS-NMS-Q has a strong association and concordance with the MDS-NMS at the total score and domain level. This indicates that the MDS-NMS-Q, allowing self-completion and focusing only on symptom severity, is an acceptable alternative to the rater- administered MDS-NMS.
Authors: K. Ray Chaudhuri, Anette Schrag, Daniel Weintraub, Alexandra Rizos, Pablo Martinez-Martin
- Acronym: MDS-NMS-Q
- Year Published: 2021
- Scale Last Updated: No updates since publication
- Estimated Time to Complete: 10 minutes
- Assessment Type: PRO
- Available translations: None
To request permission to use this Rating Scale, please fill out a Permission Request Form.
Inclusive Language in Clinical Outcome AssessmentsHealthcare providers should tailor the language used in COAs to reflect each patient’s gender identity. In grammatically gendered languages, the practice includes making appropriate linguistic adjustments to ensure communication is respectful and inclusive throughout the assessment process. |
Additional Scale Publications
Validation of the International Parkinson and Movement Disorder Society – Non-Motor Symptoms – Questionnaire (MDS-NMS-Q)
D. Weintraub, KR. Chaudhuri, A. Schrag, P. Martinez-Martin, A. Rizos, E. Mamikonyan, J. Gallagher, J. Staunton, M. Pereira Fernandes, C. Rodriguez Blazquez
October 2024
Movement Disorders 2024; 39 (suppl 1). Abstract 323.