MDS Blog

Controversies and Hot Topics in Parkinson's Disease and Movement Disorders

Welcome to the MDS Scientific Issues Committee Blog. This is a forum for visitors to obtain the latest in scientific advances, new developments, and trends in the field of Movement Disorders. Comments are welcome and please return often to read about new topics.


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Fatigue in Parkinson's Disease

Date: December 2017
Authors: Jau-Shin Lou, MD, PhD, MBA; Joseph Friedman, MD; Benzi Kluger, MD; Kelvin Chou, MD
Blog Editor: Stella Papa, MD

Fatigue in Parkinson's DiseaseFatigue is one of the most common non-motor symptoms reported in Parkinson’s disease (PD).  Up to 58% of patients with PD report symptoms of fatigue, and a third of patients claim it is their most disabling symptom. Go to Discussion

'Direct to Consumer' Genetic Testing

Date: November 2017
Authors: Prof. Enza Maria Valente, Dr. Scott Roberts, and Prof. Thomas Gasser
Blog Editor: Stella Papa, MD

'Direct to Consumer' genetic testing.In the era of digital commerce, it is not surprising to find that even genetic testing can be sold and purchased through the Internet, television, or other marketing channels without any intermediation of health care professionals and without any specific counseling, namely “Direct-To-Consumer Genetic Testing” (DTC-GT). 
Go to Discussion

Cannabinoids in Movement Disorders

Date: October 2017
Authors: Nestor Galvez-Jimenez, MD, MSc, MHA; Camilo Garcia, MD; Ramon Rodriguez, MD; Connie Marras, MD
Blog Editor: Stella Papa, MD

The use of cannabis for medical disorders is a global issue, whether or not the drug is legalized for general use, only for use in some medical disorders or not legal in any setting.The use of cannabis for medical disorders is a global issue, whether or not the drug is legalized for general use, only for use in some medical disorders or not legal in any setting.  Where not legal, there is black market selling and purchasing and large scale use in many countries.  Go to Discussion

When Does Social Media, Email and Internet Use Cross the Line to a Psychiatric Disorder?

Date: August 2017
Authors: Francisco Cardoso, MD, PhD, FAAN, and Marc N. Potenza, MD, PhD
Blog Editors: Michael S. Okun, MD, Stella Papa, MD, and Daniel Weintraub, MD
 

Psychiatrists, neurologists and general practitioners commonly encounter patients who excessively use technology. However, our understanding of when the Internet and social media habits cross a line to become a psychiatric disorder remains murky. Psychiatrists, neurologists and general practitioners commonly encounter patients who excessively use technology. However, our understanding of when the Internet and social media habits cross a line to become a psychiatric disorder remains murky.  Go to Discussion

Do-It-Yourself Transcranial Direct Current Stimulation (DIY tDCS): Is It Safe?

Date: June 2017
Authors: Jau-Shin Lou, MD, PhD, MBA; Robert Chen, MA, MBBChir, MSc, FRCPC; Velijko Dubljevic, PhD, DPhil
Blog Editors: Michael S. Okun, MD, and Stella M. Papa, MD

 

The scientific literature has shown that tDCS improves memory, math skills, and academic performance in normal subjects and may be beneficial for patients with depression, Alzheimer’s disease and stroke.The scientific literature has shown that tDCS improves memory, math skills, and academic performance in normal subjects and may be beneficial for patients with depression, Alzheimer’s disease and stroke.  Because tDCS is non-invasive, simple and low cost, it has gained significant media attention and public interest.

Go to Discussion

 

 

Autonomic Issues in Parkinson's Disease

Date: April 2017
Authors: Nestor Galvez-Jimenez, MD, MSc, MHA; Ramon Lugo-Sanchez, MD; Tarannum Khan, MD
Blog Editors: Michael S. Okun, MD, and Stella M. Pappa, MD
 

Recent advances as well as experience accrued when caring for patients with Parkinson’s’ disease (PD) has revealed that autonomic disturbances are an integral component of the evaluation of patients and that their symptoms have often become a source of disability.Recent advances as well as experience accrued when caring for patients with Parkinson’s’ disease (PD) has revealed that autonomic disturbances are an integral component of the evaluation of patients and that their symptoms have often become a source of disability.  Go to Discussion

Cognitive Problems in Parkinson's Disease

Date: March 2017
Author: Beth A. Vernaleo, PhD
Blog Editors: Michael S. Okun, MD, and Stella M. Papa, MD
 

In 2013, the Parkinson’s Disease Foundation (PDF) launched the Community Choice Research Award (CCRA), designed to advance research in areas that were identified as unmet needs within the PD community. People with Parkinson’s (PWP) and care partners (CP) were asked “what areas of research do you think scientists should be focusing on in order to make an impact in the PD community?”  In 2015, over 300 people from eight countries responded with ideas. Go to Discussion

Immunotherapies in Parkinson's Disease

Date: February 2017
Authors: Howard E. Gendelman, MD, Martin Ingelsson, Vladimir Kostić, MD, PhD, Leonidas Stefanis, MD, PhD
Blog Editors: Michael S. Okun, MD, and Stella M. Papa, MD
 

The relationship of the immune system to the pathogenesis of Parkinson’s disease (PD) and in particular to alpha-synuclein (α-syn) has been the focus of intense research efforts over many years.The relationship of the immune system to the pathogenesis of Parkinson’s disease (PD) and in particular to alpha-synuclein (α-syn) has been the focus of intense research efforts over many years.  This relationship has come recently to the forefront of interest of the PD community, as the first clinical trials in PD using immunization strategies against α-syn have commenced.  Go to Discussion.

What Do Single Gene Mutations Really Tell Us About What Goes Wrong in Idiopathic PD?

Date: December 2016
Authors: Leonidas Stefanis, MD, PhD; Thomas Gasser, MD; Roger Barker, MBBS, MRCP, PhD
Blog Editors: Michael S. Okun, MD, and Stella M. Papa, MD
 

MDS Blog: What do single gene mutations really tell us about what goes wrong in idiopathic Parkinson’s disease?Over the last 20 years there has been considerable progress in deciphering the genetic underpinnings of Parkinson’s disease (PD).  This has led to new insights into PD pathogenesis, the generation of new animal models of the disease, the implementation of experimental therapeutics in such models, and, recently, the design and initiation of clinical trials with potentially neuroprotective agents.  Go to Discussion

Psychogenic Movement Disorders in the News and on the Internet

Date: January 2017
Authors: Mark Edwards, MD, Mark Hallett, MD, Susan Jeffrey, Executive Editor, Medscape Neurology
Blog Editors: Susanne A. Schneider, MD, Michael S. Okun, MD, and Stella M. Papa, MD

Online medical news is becoming a go-to for those looking for answers to their health problems.The Internet serves as an incredible source of information. Almost any subject imaginable can be found on search engines. More recently, a plethora of social media tools have been developed and led to a change in our communication. These tools have transformed and morphed into the medical profession.  Go to Discussion

Inflammation in Parkinson's Disease

Date: March 2016
Authors: Malú Tansey, MD, David Sulzer, MD, and David Standaert, MD, PhD
Blog Editors: Michael S. Okun, MD, and Stella M. Papa, MD
 

Understanding the role of inflammation in Parkinson’s disease (PD) has attracted a large amount of interest in recent years.Understanding the role of inflammation in Parkinson’s disease (PD) has attracted a large amount of interest in recent years. Studies have identified various cellular and molecular components of the immune responses that seem to contribute to the pathology associated with α-synuclein accumulation.  Go to Discussion

Role of Physical Therapy and Exercise in Management of Parkinson's Disease

Date: October 2016
Authors: Tanya Simuni, MD, Connie Marras, MD, PhD, and Terry Ellis, PhD, PT, NCS
Blog Editors: Michael S. Okun, MD, and Stella M. Papa, MD
 

There are a growing number of randomized controlled trials and meta-analytic studies supporting the benefits of physical therapy and exercise in the treatment of Parkinson’s disease.Current pharmacological management is incompletely effective at controlling the symptoms of Parkinson’s disease and patients are often seeking complementary approaches.  Exercise is a compelling strategy since recent evidence suggests both physical and cognitive benefits and, relative to many pharmacological therapies, it is inexpensive. Go to Discussion
 

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